Computational Genomics Senior Research Scientist

Role: Senior Research Scientist in Computational Genomics at Vertex, focusing on integrating human genetics, genomics, and AI technologies to advance therapies for diseases like lung conditions and pain. Responsibilities include designing and executing genomic studies, analyzing complex datasets to inform target discovery, biomarker development, and mechanistic insights, and collaborating across disciplines to incorporate emerging computational methods. Requirements: PhD in computational biology, bioinformatics, genomics, or related, with 3+ years post-doctoral or industry experience, or Master's with 8+ years' experience; expertise in human genetic and NGS data analysis, proficiency in programming (R, Python), Unix/Linux, and high-performance computing; solid understanding of genetics and disease biology. Preferred: experience applying machine learning and AI in genomics research. High-Value: focus on human genetics and genomics in drug discovery, with a role in translational research and data interpretation, supporting therapeutics development for serious diseases. Work setup: hybrid or on-site in San Diego, CA, with at least three days on-site.