Computational Chemistry Research Scientist (Computational Drug Design)

Role: Computational Chemist in Vertex's Drug Design group, focusing on hit/lead identification and optimization using molecular modeling, cheminformatics, data science, and AI. Responsibilities: apply computational methods to accelerate drug discovery, collaborate with cross-disciplinary teams, develop new workflows, and enhance computational capabilities. Qualifications: Ph.D. in Computational Chemistry or related field; 0-3 years' experience; expertise in structure-based drug design, AI tools, Python scripting, and familiarity with drug discovery concepts. High-Value: focus on small molecules, biologics, or gene therapies; early to late-stage development; cross-functional collaboration with Chemistry, Biology, DMPK, Structural Biology; emphasis on innovative AI applications. Work Setup: hybrid or on-site in Boston, with flexible work arrangements.