Computational Biologist I

Role: Computational Biologist I focusing on bioinformatics method development and genomic signature discovery in oncology, primarily analyzing DNA methylation data. Responsibilities: develop biomarkers and signatures using large-scale datasets, investigating cancer epigenetics; perform statistical analysis, optimize NGS assay performance; collaborate with R&D, medical, regulatory, and external partners; design bioinformatics algorithms, maintain cloud-based data infrastructure, and ensure data quality; contribute to scientific publications and presentations. Requirements: PhD or Master’s with relevant research experience in cancer biology, bioinformatics, or related fields; 6+ years (Bachelor’s) or 2+ years (Master’s) in industry or post-doc; proficiency in Unix, Python, R, SQL; experience analyzing methylation data and working with public datasets; knowledge of NGS principles and cloud platforms like AWS; effective communication skills. Preferred: industry/post-doc experience in cancer bioinformatics, familiarity with genomic data analysis, version control, and HIPAA compliance. High-Value: focus on DNA methylation, cancer epigenetics, NGS assay development, large genomic datasets, and interdisciplinary collaboration. Location: Boston; salary range: $112,560–$133,000; other benefits include discretionary bonus.