Caris Life Sciences logo

Clinical Systems Architect

Caris Life Sciences
Full-time
Remote friendly (Irving, TX)
United States
IT

Want to see how your resume matches up to this job? A free trial of our JobsAI will help! With over 2,000 biopharma executives loving it, we think you will too! Try it now — JobsAI.

Role Summary

We are seeking a Clinical Systems Architect with strong Architecture and DevOps expertise to serve as a technical bridge between application development and IT infrastructure teams. This role requires deep knowledge of CI/CD pipelines, information security, networking, and cloud operations, while maintaining strong full-stack development capabilities. The ideal candidate will collaborate with Software Engineers, Architects, Engineering Managers, Product Managers, and IT teams to deliver secure, scalable, and high-availability solutions.

Responsibilities

  • Lead the design and implementation of CI/CD pipelines with automated deployment strategies, SAST/DAST scanning, and infrastructure as code
  • Architect and maintain cloud-native solutions across AWS, GCP, or Azure, ensuring optimal performance and cost efficiency
  • Implement and manage security guardrails including authentication mechanisms, encryption protocols, and compliance frameworks (HIPAA, OIDC/OAuth 2.0)
  • Design and optimize networking solutions for high-availability, load balancing, and secure data transmission
  • Develop full-stack applications using Python and/or Node.js/Next.js with Vue.js or React
  • Integrate with monitoring and observability tools (Sentry, Datadog, NewRelic, Grafana) for comprehensive application performance management
  • Implement containerization strategies using Docker and Kubernetes for scalable deployments
  • Design and maintain RESTful APIs with security-first principles
  • Serve as the primary liaison between application development and IT teams (Networking, InfoSec, Cloud Operations)
  • Automate infrastructure provisioning and deployment processes using DevOps methodologies
  • Implement security scanning and monitoring throughout the development lifecycle
  • Collaborate with cloud operations teams to ensure seamless releases and incident response
  • Monitor incident tickets and determine resolution priority
  • Perform code reviews and offer constructive feedback
  • Provide technical/engineering support for existing applications, including code fixes
  • Analyze and solve complex technical problems, ensuring code quality, performance, and scalability
  • Collaborate with other departments (product management, quality assurance) for seamless product delivery
  • Assist management with timelines, resource estimates, and delivery details
  • Mentor and coach junior developers
  • Perform other related duties as assigned

Qualifications

  • Required: Bachelor's degree in Computer Science, Software Engineering, or related field
  • Required: 5-7 years of DevOps & Infrastructure experience including expert-level proficiency in CI/CD methodologies and pipeline automation
  • Required: 5-7 years of Programming & Development experience with advanced Python programming and JavaScript/TypeScript expertise including Node.js, Vue.js, or React
  • Required: Strong experience with containerization (Docker, Kubernetes preferred)
  • Required: Proven track record in cloud architecture (AWS Lambda, SNS/SQS, S3, or equivalent GCP/Azure services)
  • Required: Comprehensive understanding of networking principles and security protocols
  • Required: Database design and optimization (MySQL, PostgreSQL, ORM technologies)
  • Required: API design and security implementation (REST, authentication, encryption)
  • Required: Deep knowledge of information security best practices and implementation
  • Required: Experience with security scanning tools (SAST/DAST) and vulnerability management
  • Required: Understanding of compliance frameworks (HIPAA, SOC 2, etc.)
  • Required: Proficiency in implementing security protocols (OIDC/OAuth 2.0, encryption)
  • Required: Version control systems (Git) and collaborative development workflows
  • Required: Monitoring and alerting platforms (Grafana, Sentry, Datadog, NewRelic)
  • Required: Infrastructure automation and configuration management
  • Required: Performance optimization and scalability planning
  • Required: Excellent problem-solving skills, analytical thinking, strong communication skills, and ability to work collaboratively in team-oriented environments

Preferred Qualifications

  • Experience with AI-assisted development tools (Cursor AI)
  • Advanced networking and security certifications (CISSP, CCNA, AWS Security)
  • Experience with service mesh technologies and microservices architecture
  • Knowledge of data pipeline architecture and ETL processes
  • Experience with incident response and disaster recovery planning
  • Demonstrated capability to independently diagnose, analyze, and resolve complex issues related to application software
  • Skilled in ensuring HIPAA compliance, improving patient outcomes, and maintaining quality assurance standards while adhering to regulatory requirements

Physical Demands

  • Ability to sit, stand, and work at a computer for extended periods

Training

  • All job-specific, safety, and compliance training assigned based on job functions

Other

  • This position requires periodic travel and flexible availability, including some evenings, weekends, and/or holidays.
  • The role may require after-hours response to emergency issues. There are also occasionally scheduled on-call duties that necessitate responding to technical emergencies beyond assigned job responsibilities.