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Clinical Program Manager

Revolution Medicines
August 21, 2026
Full-time
On-site
San Francisco Bay Area
Clinical Research and Development
Role: Clinical Program Manager (CPM) overseeing clinical trial execution for Revolution Medicines' oncology pipeline targeting RAS-mutant cancers. Responsibilities: lead cross-functional study teams, manage vendor relationships, ensure compliance with GCP/ICH/FDA standards, develop study documentation, track program metrics, and mitigate risks. Lead larger, complex trials with some oversight, mentor junior staff, and contribute to SOP development. Requirements: RN or BSc/Master in biological sciences or health-related field; 8+ years in clinical operations or research, including 4+ years leading study teams; strong knowledge of FDA, GCP, ICH guidelines; experience managing CROs/vendors; proficient in clinical trial documentation and project management tools. Preferred: familiarity with oncology, early/late-stage clinical operations, and international trial management; experience with eTMF, EDC, CTMS systems; mentoring experience. High-Value: oncology, RAS mutation indications, late-stage clinical trials, vendor/contract management, cross-functional leadership, and international trial experience. WorkSetup: on-site at Redwood City, CA with ~25% travel.