Clinical Program Leader (CPL)

Role: Senior or Lead Clinical Oncology Physician (CPL) providing strategic medical guidance for experimental oncology agents from preclinical entry through Transition Decision Point (TDP). Responsibilities: develop and lead clinical development strategies integrating preclinical data, collaborate across disciplines to optimize development plans, design clinical protocols, and support early clinical trials for small molecules, biologics, and radioligand therapies. Liaise with external experts and regulators, contribute to publications, and ensure compliance with GCP and internal standards. Qualifications: MD or DO with Board certification in oncology; PhD preferred. Minimum 2+ years in industry or academic translational oncology, with expertise in clinical trial design, oncology pharmacology, PK/PD, biostatistics, and regulatory requirements. External recognition as an oncology expert and strong publication record desirable. High-Value: Oncology (preclinical through early clinical), biologics and small molecules, combination therapies, GxP compliance, global project leadership, fluency in English, hybrid onsite in Cambridge, MA, with a focus on strategic leadership and cross-functional collaboration.