Clinical Program Lead (CPL) - RLT Focus
Novartis
September 02, 2026
Full-time
Remote friendly (Cambridge, MA)
Worldwide
Clinical Research and Development
Role: Provide strategic medical and scientific leadership for the development of experimental oncology agents (small molecules, biologics, radioligand therapies) from preclinical development (Portfolio Entry/Drug Candidate) through Transition Decision Point (TDP). Responsibilities: develop integrated clinical development strategies, interpret preclinical data, collaborate on protocol design, ensure compliance with GCP and regulatory standards, liaise with external experts and authorities, and support publication efforts. May lead multiple global project teams and mentor junior staff. Qualifications: MD or DO, with preferred board certification in oncology and PhD. Requires at least 2 years of industry or academic experience in oncology clinical trials, with expertise in translational oncology, RLT preferred. Strong knowledge of pharmacology, pharmacokinetics, biostatistics, and GxP is essential. Recognized external expertise, excellent communication, strategic thinking, and leadership skills are expected. High-value specifics: Oncology (including RLT), preclinical to TDP phases, early clinical development strategy, global project team leadership. Location: Cambridge, MA, hybrid; local candidates preferred; may consider DWA. Travel: Not specified.