Clinical Pharmacology Lead (Associate Director)
Pfizer
September 23, 2026
Full-time
Remote friendly (Cambridge, MA)
Worldwide
Clinical Research and Development
Role: Associate Director of Clinical Pharmacology within Pfizer's Internal Medicine portfolio, focusing on model-informed drug discovery and development (MIDD). Responsibilities: lead clinical pharmacology strategies, design and oversee pharmacokinetic/pharmacodynamic (PK/PD) plans, contribute to clinical development plans and regulatory documents, and utilize innovative modeling methods to optimize dosing regimens. Collaborate across multifunctional teams, including clinical, statistical, and regulatory groups, to ensure integrated knowledge application, robust study designs, and successful regulatory interactions. Requirements: MD or PhD with 5+ years industry experience in clinical pharmacology, pharmacometrics, or systems pharmacology; expertise in PK/PD modeling, familiarity with tools like NONMEM and R; strong leadership, influencing, and communication skills. High-Value: focus on internal medicine, model-informed drug development, PK/PD integration, regulatory contributions (IND, NDA/MAA), and innovative quantitative methods. Work Setup: hybrid role with onsite presence required, within commuting distance; travel as needed.