Clinical Pharmacologist II
Vertex Pharmaceuticals
6 months ago
Remote friendly (Boston, MA)
United States
Clinical Research and Development
General Summary:
- Design, conduct, analyze, and report on clinical pharmacology studies.
- Work collaboratively across cross-functional study teams; complete assigned work in a resourceful, self-sufficient manner; develop alternative approaches when needed.
- Effectively communicate through verbal and written communication.
Key Duties and Responsibilities:
- Provide informed perspective on metabolic, co-dosing, and drug-drug interaction issues.
- Initiate protocol concepts and guide protocol start-up (site initiations and investigator meetings).
- Perform PK, PK/PD, or exploratory analyses.
- Prepare analytical reports, including clinical study reports.
- Contribute to clinical pharmacology summary documents.
- Collaborate and/or co-direct modeling plans.
- Assist in contract research organization (CRO) management.
- Implement novel clinical pharmacology methodology for study design and/or analysis.
- Stay current with relevant scientific literature within clinical pharmacology.
Knowledge and Skills:
- Apply critical thinking with strong scientific and development judgment.
- Communicate clearly (verbal and written).
- Supervise or conduct clinical studies (e.g., drug-drug interaction, special populations, bioavailability).
- Understand cross-functional needs; develop critical rationale; collaborate and drive innovation.
- Conduct non-compartmental pharmacokinetic (PK) and PK/pharmacodynamic analyses.
- Work collaboratively on cross-functional teams.
Education and Experience:
- Ph.D. or Pharm D (or equivalent) in pharmacokinetics, pharmacometrics, clinical pharmacology, or translational development, with 0 years of relevant post-doctoral experience; or
- Master’s degree (or equivalent) in pharmacokinetics, pharmacometrics, clinical pharmacology, or translational development, with 4+ years of relevant employment experience.
Pay / Benefits (as stated):
- Pay range: $128,300 - $192,500.
- Eligible for annual bonus and annual equity awards.
- Annual paid time off (including a week-long company shutdown in the Summer and the Winter), medical/dental/vision, educational assistance (student loan repayment), commuting subsidy, matching charitable donations, and 401(k).
Flex designation (as stated):
- Remote-Eligible: choose Remote (remote five days/week with occasional office visits), Hybrid (remote up to two days/week), or On-Site (five days/week on-site with ad hoc flexibility).
Application/Contact:
- Contact Talent Acquisition at ApplicationAssistance@vrtx.com for accommodation requests related to the hiring process or job performance.
- Design, conduct, analyze, and report on clinical pharmacology studies.
- Work collaboratively across cross-functional study teams; complete assigned work in a resourceful, self-sufficient manner; develop alternative approaches when needed.
- Effectively communicate through verbal and written communication.
Key Duties and Responsibilities:
- Provide informed perspective on metabolic, co-dosing, and drug-drug interaction issues.
- Initiate protocol concepts and guide protocol start-up (site initiations and investigator meetings).
- Perform PK, PK/PD, or exploratory analyses.
- Prepare analytical reports, including clinical study reports.
- Contribute to clinical pharmacology summary documents.
- Collaborate and/or co-direct modeling plans.
- Assist in contract research organization (CRO) management.
- Implement novel clinical pharmacology methodology for study design and/or analysis.
- Stay current with relevant scientific literature within clinical pharmacology.
Knowledge and Skills:
- Apply critical thinking with strong scientific and development judgment.
- Communicate clearly (verbal and written).
- Supervise or conduct clinical studies (e.g., drug-drug interaction, special populations, bioavailability).
- Understand cross-functional needs; develop critical rationale; collaborate and drive innovation.
- Conduct non-compartmental pharmacokinetic (PK) and PK/pharmacodynamic analyses.
- Work collaboratively on cross-functional teams.
Education and Experience:
- Ph.D. or Pharm D (or equivalent) in pharmacokinetics, pharmacometrics, clinical pharmacology, or translational development, with 0 years of relevant post-doctoral experience; or
- Master’s degree (or equivalent) in pharmacokinetics, pharmacometrics, clinical pharmacology, or translational development, with 4+ years of relevant employment experience.
Pay / Benefits (as stated):
- Pay range: $128,300 - $192,500.
- Eligible for annual bonus and annual equity awards.
- Annual paid time off (including a week-long company shutdown in the Summer and the Winter), medical/dental/vision, educational assistance (student loan repayment), commuting subsidy, matching charitable donations, and 401(k).
Flex designation (as stated):
- Remote-Eligible: choose Remote (remote five days/week with occasional office visits), Hybrid (remote up to two days/week), or On-Site (five days/week on-site with ad hoc flexibility).
Application/Contact:
- Contact Talent Acquisition at ApplicationAssistance@vrtx.com for accommodation requests related to the hiring process or job performance.