Clinical Director (Principal Scientist), Translational Medicine, Immunology
Merck
13 days ago
Remote friendly (Boston, MA)
United States
Clinical Research and Development
Translational Medicine is responsible for early clinical development of novel therapeutics with the role focused on Immunology.
Principal Scientist (Medical Director level; known internally as Clinical Directors) with strong background in basic and/or clinical translational research and collaborative cross-therapeutic-area experience.
Responsibilities:
- Lead early clinical development strategy from Preclinical Candidate approval through Phase 1 clinical pharmacology testing and Phase 2 clinical proof-of-concept.
- Develop biomarker strategies with cross-functional teams, including experimental medicine studies to establish/validate biomarker platforms.
- Partner with discovery research to bring clinical perspective into target identification/validation; execute clinical studies to evaluate target relevance to human disease.
- Develop and execute clinical pharmacology strategies from Phase 2 proof-of-concept through worldwide marketing application.
- Provide clinical expertise, including design of preclinical and/or clinical pharmacology experiments to validate targets/pathways.
- Ensure safe/timely Phase 1 study execution; collaborate with internal/external clinical support and scientific teams.
- Provide clinical pharmacology support for regulatory filing through registration documents and presentations.
- Communicate and interpret study results to governance/experts/review committees.
- Interface broadly with key functions across global research sites.
Education: MD or MD/PhD.
Required:
- Track record in clinical medicine or clinical research; biomedical research background.
- Scientific scholarship/achievement (publications or presentations) and collaborative mindset.
- Strong interpersonal, writing, and presentation skills.
Preferred:
- Clinical board certification or eligibility.
- Prior translational research and/or early clinical development experience.
- Track record in clinical care or management of clinical problem-solving.
Required skills: Clinical Development, Clinical Judgment, Clinical Research/Studies/Trials, Clinical Trial Support, Early Clinical Development, Immunology, Intellectual Curiosity, Translational Medicine/Research, Cross-Functional Teamwork.
Application: Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub).
Principal Scientist (Medical Director level; known internally as Clinical Directors) with strong background in basic and/or clinical translational research and collaborative cross-therapeutic-area experience.
Responsibilities:
- Lead early clinical development strategy from Preclinical Candidate approval through Phase 1 clinical pharmacology testing and Phase 2 clinical proof-of-concept.
- Develop biomarker strategies with cross-functional teams, including experimental medicine studies to establish/validate biomarker platforms.
- Partner with discovery research to bring clinical perspective into target identification/validation; execute clinical studies to evaluate target relevance to human disease.
- Develop and execute clinical pharmacology strategies from Phase 2 proof-of-concept through worldwide marketing application.
- Provide clinical expertise, including design of preclinical and/or clinical pharmacology experiments to validate targets/pathways.
- Ensure safe/timely Phase 1 study execution; collaborate with internal/external clinical support and scientific teams.
- Provide clinical pharmacology support for regulatory filing through registration documents and presentations.
- Communicate and interpret study results to governance/experts/review committees.
- Interface broadly with key functions across global research sites.
Education: MD or MD/PhD.
Required:
- Track record in clinical medicine or clinical research; biomedical research background.
- Scientific scholarship/achievement (publications or presentations) and collaborative mindset.
- Strong interpersonal, writing, and presentation skills.
Preferred:
- Clinical board certification or eligibility.
- Prior translational research and/or early clinical development experience.
- Track record in clinical care or management of clinical problem-solving.
Required skills: Clinical Development, Clinical Judgment, Clinical Research/Studies/Trials, Clinical Trial Support, Early Clinical Development, Immunology, Intellectual Curiosity, Translational Medicine/Research, Cross-Functional Teamwork.
Application: Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub).