Clinical Development Senior Medical Director, Oncology
Pfizer
August 17, 2026
Remote friendly (San Diego, CA)
United States
Clinical Research and Development
Job Summary
The Senior Medical Director provides clinical development expertise for late-stage thoracic oncology clinical trials, overseeing design, conduct, and analysis, and may supervise other medical directors. Works with regulatory affairs, pharmacovigilance, biostatistics, and medical affairs; provides guidance to clinical operations, investigators, and external stakeholders.
Responsibilities
- Conduct medical monitoring: eligibility assessment, data review, safety monitoring.
- Lead peer-to-peer interactions with investigators.
- Serve as point of contact for clinical issues between study team, investigators, ethics/steering committees, and regulatory authorities.
- Lead and maintain clinical trial and regulatory documents with Clinical Scientist and cross-functional team.
- Execute clinical development strategies as part of the Clinical Subteam (Global Product Team).
- Represent the company in external engagements (advisory boards, health authority interactions).
- Review/interpret clinical data, identify key findings/implications, and communicate to stakeholders.
- Stay current on literature and guidelines to advise and drive development plans.
Qualifications/Required
- Medical degree required.
- 5+ years industry experience required.
- Clinical Development experience required.
- Primary medical degree (MD/DO/MBBS/MBChB) from a recognized institution.
- Licensed to prescribe medicines independently for at least 2 years after intern/house officer/foundation period.
Preferred
- Late-stage clinical development; Thoracic Oncology.
- Board certified/eligible in oncology.
- Maintained medical license in good standing.
Work & Compensation
- Hybrid: live within commuting distance; ~2.5 on-site days/week.
- Travel to meetings several times/year.
- Relocation assistance may be provided.
- Base salary: $274,500–$457,500; bonus target 25%; eligible for share-based incentives; comprehensive benefits include 401(k) with company match, paid leave, and medical/dental/vision.
The Senior Medical Director provides clinical development expertise for late-stage thoracic oncology clinical trials, overseeing design, conduct, and analysis, and may supervise other medical directors. Works with regulatory affairs, pharmacovigilance, biostatistics, and medical affairs; provides guidance to clinical operations, investigators, and external stakeholders.
Responsibilities
- Conduct medical monitoring: eligibility assessment, data review, safety monitoring.
- Lead peer-to-peer interactions with investigators.
- Serve as point of contact for clinical issues between study team, investigators, ethics/steering committees, and regulatory authorities.
- Lead and maintain clinical trial and regulatory documents with Clinical Scientist and cross-functional team.
- Execute clinical development strategies as part of the Clinical Subteam (Global Product Team).
- Represent the company in external engagements (advisory boards, health authority interactions).
- Review/interpret clinical data, identify key findings/implications, and communicate to stakeholders.
- Stay current on literature and guidelines to advise and drive development plans.
Qualifications/Required
- Medical degree required.
- 5+ years industry experience required.
- Clinical Development experience required.
- Primary medical degree (MD/DO/MBBS/MBChB) from a recognized institution.
- Licensed to prescribe medicines independently for at least 2 years after intern/house officer/foundation period.
Preferred
- Late-stage clinical development; Thoracic Oncology.
- Board certified/eligible in oncology.
- Maintained medical license in good standing.
Work & Compensation
- Hybrid: live within commuting distance; ~2.5 on-site days/week.
- Travel to meetings several times/year.
- Relocation assistance may be provided.
- Base salary: $274,500–$457,500; bonus target 25%; eligible for share-based incentives; comprehensive benefits include 401(k) with company match, paid leave, and medical/dental/vision.