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Clinical Development Senior Medical Director, Oncology

Pfizer
August 17, 2026
Remote friendly (Cambridge, MA)
United States
Clinical Research and Development
Job Responsibilities
- Provide clinical development expertise for late-stage thoracic oncology clinical trials, including oversight of study design, conduct, and analysis; may supervise (associate) medical directors.
- Conduct medical monitoring (eligibility assessment, data review, safety monitoring).
- Lead peer-to-peer interactions with investigators.
- Serve as point of contact for clinical issues between study team, investigators, ethics/steering committees, and regulatory authorities.
- Lead/contribute to development and maintenance of clinical trial and regulatory documents with Clinical Scientist and cross-functional teams.
- Execute clinical development strategies as part of the Clinical Subteam of the Global Product Team.
- Represent the company externally (advisory boards, health authority interactions).
- Review and interpret clinical data, identify key findings, and communicate to internal/external stakeholders.
- Stay current on literature and guidelines to advise and drive clinical development plans.

Qualifications (Required)
- Medical degree required.
- 5+ years industry experience required.
- Clinical Development experience required.
- MQI: primary medical degree (MD/DO/MBBS/MBChB) and licensed to prescribe independently for at least 2 years post-intern/house officer/foundation.

Preferred Qualifications
- Late-stage clinical development; Thoracic Oncology; board certified/eligible in oncology or equivalent; maintained medical license in good standing.

Work Requirements
- Hybrid: live within commuting distance; work on-site ~2.5 days/week; travel to conferences/meetings several times/year.
- U.S. work authorization required; visa sponsorship not available.

Compensation/Benefits
- Base salary: $274,500–$457,500; bonus target 25%; eligibility for share-based long-term incentive; 401(k) with matching contributions and additional retirement contribution; paid vacation/holidays/personal days; caregiver/parental and medical leave; medical/prescription/dental/vision coverage.

Relocation
- Relocation assistance may be provided.