Clinical Development Medical Director-Nephrology
Vertex Pharmaceuticals
August 07, 2026
Remote friendly (Boston, MA)
United States
Clinical Research and Development
General Summary:
- Serve as Medical Lead for clinical trials; oversee study execution and act as internal primary Medical Monitor for subject safety and scientific integrity.
- May participate in other clinical development projects.
Key Duties And Responsibilities:
- Develop study protocols, investigator’s brochures, clinical development plans and key documents with minimal guidance.
- Serve on cross-functional Study Execution Teams (SET) for assigned trials.
- Prepare regulatory documents (e.g., IND/CTA clinical sections, IND safety and annual reports, responses to authorities and Ethics Committees/IRBs).
- Provide scientific/clinical input to study documents and analysis plans (informed consent, clinical research forms, SAPs, clinical pharmacology plans, clinical study reports).
- Liaison between Clinical Development and internal groups (e.g., Regulatory Affairs).
- Represent the company to outside medical personnel regarding protocols, study conduct, and external reporting.
Knowledge And Skills:
- Strong oral/written communication; collaborate in matrix environments; work independently.
- Global clinical research and regulatory authority interaction (plus).
- Familiarity with research data, biostatistics, pharmacology/pharmacokinetics, GCP, study design, ethics/IRB review, and scientific communication (manuscripts/abstracts/posters/oral presentations).
- Board certification/eligibility and clinical training in a relevant specialty (highly desired).
Education And Experience:
- MD/DO or equivalent ex-US medical degree.
- Typically 8 years basic/clinical research in academic/industry or equivalent.
Compensation:
- Pay range: $204,000 - $306,000; eligible for annual bonus and annual equity awards.
Flex Designation:
- Hybrid-eligible or On-Site eligible (remote up to two days/week for Hybrid).
- Serve as Medical Lead for clinical trials; oversee study execution and act as internal primary Medical Monitor for subject safety and scientific integrity.
- May participate in other clinical development projects.
Key Duties And Responsibilities:
- Develop study protocols, investigator’s brochures, clinical development plans and key documents with minimal guidance.
- Serve on cross-functional Study Execution Teams (SET) for assigned trials.
- Prepare regulatory documents (e.g., IND/CTA clinical sections, IND safety and annual reports, responses to authorities and Ethics Committees/IRBs).
- Provide scientific/clinical input to study documents and analysis plans (informed consent, clinical research forms, SAPs, clinical pharmacology plans, clinical study reports).
- Liaison between Clinical Development and internal groups (e.g., Regulatory Affairs).
- Represent the company to outside medical personnel regarding protocols, study conduct, and external reporting.
Knowledge And Skills:
- Strong oral/written communication; collaborate in matrix environments; work independently.
- Global clinical research and regulatory authority interaction (plus).
- Familiarity with research data, biostatistics, pharmacology/pharmacokinetics, GCP, study design, ethics/IRB review, and scientific communication (manuscripts/abstracts/posters/oral presentations).
- Board certification/eligibility and clinical training in a relevant specialty (highly desired).
Education And Experience:
- MD/DO or equivalent ex-US medical degree.
- Typically 8 years basic/clinical research in academic/industry or equivalent.
Compensation:
- Pay range: $204,000 - $306,000; eligible for annual bonus and annual equity awards.
Flex Designation:
- Hybrid-eligible or On-Site eligible (remote up to two days/week for Hybrid).