Clinical Development Leader, Movement Disorders
Praxis Precision Medicines, Inc.
August 20, 2026
Remote friendly (Boston, MA)
United States
Clinical Research and Development
Location/Work Model:
- May be performed remotely; requires flexibility and willingness to travel as needed.
Primary Responsibilities:
- Movement disorders development: Apply deep knowledge of the disease area, endpoints, rating instruments, and patient experience to development strategy and decisions.
- Clinical strategy and trials: Translate science, emerging data, patient need, and regulatory requirements into development strategies; personally lead studies from design through execution.
- Data-driven decisions: Interpret emerging clinical/scientific data and make timely calls when information is incomplete.
- Regulatory strategy: Own substantive clinical content for regulatory filings, briefing materials, and health authority interactions.
- Cross-functional leadership: Lead teams across clinical operations, biostatistics, regulatory, safety, and other disciplines to resolve issues and move programs forward.
- External leadership: Represent the company with investigators, KOLs, health authorities, and partners.
Qualifications/Key Success Factors:
- Advanced scientific degree (MD, PharmD, PhD, or equivalent) required.
- Track record of personally led clinical trials, programs, submissions, or major development decisions.
- Regulatory submissions ownership: led clinical content for IND/CTA/NDA/MAA filings, briefing books, and health authority interactions.
- Strong judgment; ability to escalate and make thoughtful, timely decisions on emerging data.
- Comfortable in a dynamic, small organization where priorities shift.
Compensation & Benefits (as stated):
- Annualized base salary: $280,000–$350,000 USD.
- Benefits include 99% premium paid for medical/dental/vision; company-paid life insurance, AD&D, disability; 401(k) match up to 6%; long-term stock incentives and ESPP; discretionary quarterly bonus; flexible wellness benefit; generous PTO; paid holidays and company-wide shutdowns.
- May be performed remotely; requires flexibility and willingness to travel as needed.
Primary Responsibilities:
- Movement disorders development: Apply deep knowledge of the disease area, endpoints, rating instruments, and patient experience to development strategy and decisions.
- Clinical strategy and trials: Translate science, emerging data, patient need, and regulatory requirements into development strategies; personally lead studies from design through execution.
- Data-driven decisions: Interpret emerging clinical/scientific data and make timely calls when information is incomplete.
- Regulatory strategy: Own substantive clinical content for regulatory filings, briefing materials, and health authority interactions.
- Cross-functional leadership: Lead teams across clinical operations, biostatistics, regulatory, safety, and other disciplines to resolve issues and move programs forward.
- External leadership: Represent the company with investigators, KOLs, health authorities, and partners.
Qualifications/Key Success Factors:
- Advanced scientific degree (MD, PharmD, PhD, or equivalent) required.
- Track record of personally led clinical trials, programs, submissions, or major development decisions.
- Regulatory submissions ownership: led clinical content for IND/CTA/NDA/MAA filings, briefing books, and health authority interactions.
- Strong judgment; ability to escalate and make thoughtful, timely decisions on emerging data.
- Comfortable in a dynamic, small organization where priorities shift.
Compensation & Benefits (as stated):
- Annualized base salary: $280,000–$350,000 USD.
- Benefits include 99% premium paid for medical/dental/vision; company-paid life insurance, AD&D, disability; 401(k) match up to 6%; long-term stock incentives and ESPP; discretionary quarterly bonus; flexible wellness benefit; generous PTO; paid holidays and company-wide shutdowns.