Clinical Development Executive Medical Director, Thoracic
Pfizer
August 25, 2026
Remote friendly (San Diego, CA)
United States
Clinical Research and Development
Clinical Development Medical Executive Director (Thoracic Cancers)
Responsibilities:
- Define and execute clinical development strategy for oncology program(s) in alignment with Lifecycle Management Plan and Integrated Product Plan.
- Lead product specific Global Development Team (GDT) and/or serve as clinical lead across multiple clinical trials.
- Serve as subject matter expert on clinical issues; endorse clinical decisions with Global Development Product Lead (GDPL) and governance bodies.
- Accountable for clinical development strategy, trial design, execution, and delivery of trial results with GDPL.
- Integrate regulatory, statistical, and stakeholder input into study designs.
- Primary interface with Development Review Committee.
- Oversee clinical protocols and amendments, investigator brochures, and clinical study reports.
- Oversee evaluation, interpretation, reporting, and presentation of study data.
- Accountable for safety decisions and clinical evaluations; coordinate with clinical pharmacology for optimal dose/schedule selection.
- Accountable for regulatory interactions with health authorities (as needed); serve as point of contact among study team, investigators, ethics/steering committees, and regulators.
- Conduct medical monitoring (eligibility assessment, data review, safety monitoring); lead peer-to-peer interactions with investigators.
- Lead and contribute to development/maintenance of clinical and regulatory documents with Clinical Scientist and cross-functional team.
- Participate in business development opportunity evaluation; serve on working groups including for Marketing Authorization Applications.
Qualifications (Basic):
- Medical degree or advanced degree with relevant clinical/industry experience (typically 5+ years).
- Licensed/registered to prescribe medicines independently for at least 2 years.
- 5+ years leading diverse teams.
- Prior management responsibilities of medical directors or clinical scientists.
- Late phase drug development experience.
Preferred:
- Board certified/eligible in oncology (or equivalent).
- Experience in thoracic cancer and/or immuno-oncology trials.
- Experience across multiple oncology phases and drug classes.
- Experience leading NDA/BLA/MAA.
Benefits/Relocation:
- Relocation support available.
Work location:
- Hybrid; commute distance; on-site ~2.5 days/week.
Application instructions:
- Not specified in provided text.
Responsibilities:
- Define and execute clinical development strategy for oncology program(s) in alignment with Lifecycle Management Plan and Integrated Product Plan.
- Lead product specific Global Development Team (GDT) and/or serve as clinical lead across multiple clinical trials.
- Serve as subject matter expert on clinical issues; endorse clinical decisions with Global Development Product Lead (GDPL) and governance bodies.
- Accountable for clinical development strategy, trial design, execution, and delivery of trial results with GDPL.
- Integrate regulatory, statistical, and stakeholder input into study designs.
- Primary interface with Development Review Committee.
- Oversee clinical protocols and amendments, investigator brochures, and clinical study reports.
- Oversee evaluation, interpretation, reporting, and presentation of study data.
- Accountable for safety decisions and clinical evaluations; coordinate with clinical pharmacology for optimal dose/schedule selection.
- Accountable for regulatory interactions with health authorities (as needed); serve as point of contact among study team, investigators, ethics/steering committees, and regulators.
- Conduct medical monitoring (eligibility assessment, data review, safety monitoring); lead peer-to-peer interactions with investigators.
- Lead and contribute to development/maintenance of clinical and regulatory documents with Clinical Scientist and cross-functional team.
- Participate in business development opportunity evaluation; serve on working groups including for Marketing Authorization Applications.
Qualifications (Basic):
- Medical degree or advanced degree with relevant clinical/industry experience (typically 5+ years).
- Licensed/registered to prescribe medicines independently for at least 2 years.
- 5+ years leading diverse teams.
- Prior management responsibilities of medical directors or clinical scientists.
- Late phase drug development experience.
Preferred:
- Board certified/eligible in oncology (or equivalent).
- Experience in thoracic cancer and/or immuno-oncology trials.
- Experience across multiple oncology phases and drug classes.
- Experience leading NDA/BLA/MAA.
Benefits/Relocation:
- Relocation support available.
Work location:
- Hybrid; commute distance; on-site ~2.5 days/week.
Application instructions:
- Not specified in provided text.