Clinical Development Director, Early Development Oncology
Amgen
August 26, 2026
Remote friendly (United States)
United States
Clinical Research and Development
Clinical Development Director
Responsibilities:
- Lead early phase clinical development of oncology compounds from first-in-human through proof-of-concept.
- Collaborate to design and deliver early phase clinical trials.
- Support protocol development, study start up, data review, monitoring, and analysis.
- Contribute to early clinical development strategy; prepare clinical development plans, clinical study protocols, informed consents, Investigator Brochures, and ethics/regulatory submissions.
- Review and evaluate safety, efficacy, pharmacodynamic, and pharmacokinetic data.
- Develop strategy for clinical biomarkers to facilitate drug development.
- Collaborate with Precision Medicine, Research, Late Development, Regulatory, Safety, and Commercial colleagues.
- Evaluate external licensing/partnering opportunities in oncology.
- Provide biomedical expertise and strategic guidance to oncology early development teams.
Basic Qualifications:
- MD or DO from an accredited medical school.
- 2 years of industry or academic clinical research/drug development experience.
Preferred Qualifications:
- Board certified/eligible (Oncology); oncology residency training.
- Experience in basic research and/or clinical trial methodology.
- 3+ years drug development experience (preferably early stage trials).
- Experience collaborating with pharmaceutical sponsors.
- Experience designing, monitoring, implementing clinical trials, and interpreting results.
- Leadership, matrix decision-making/alignment, publication track record.
- Excellent interpersonal and presentation skills.
Benefits:
- Comprehensive employee benefits package, retirement/savings plan (company contributions), medical/dental/vision, life/disability insurance, flexible spending accounts.
- Discretionary annual bonus (or field sales incentive), stock-based long-term incentives, time-off plans, flexible work models (where possible).
Application Instructions:
- Apply via careers.amgen.com; no application deadline—applications continue until a sufficient number are received or a candidate is selected.
Responsibilities:
- Lead early phase clinical development of oncology compounds from first-in-human through proof-of-concept.
- Collaborate to design and deliver early phase clinical trials.
- Support protocol development, study start up, data review, monitoring, and analysis.
- Contribute to early clinical development strategy; prepare clinical development plans, clinical study protocols, informed consents, Investigator Brochures, and ethics/regulatory submissions.
- Review and evaluate safety, efficacy, pharmacodynamic, and pharmacokinetic data.
- Develop strategy for clinical biomarkers to facilitate drug development.
- Collaborate with Precision Medicine, Research, Late Development, Regulatory, Safety, and Commercial colleagues.
- Evaluate external licensing/partnering opportunities in oncology.
- Provide biomedical expertise and strategic guidance to oncology early development teams.
Basic Qualifications:
- MD or DO from an accredited medical school.
- 2 years of industry or academic clinical research/drug development experience.
Preferred Qualifications:
- Board certified/eligible (Oncology); oncology residency training.
- Experience in basic research and/or clinical trial methodology.
- 3+ years drug development experience (preferably early stage trials).
- Experience collaborating with pharmaceutical sponsors.
- Experience designing, monitoring, implementing clinical trials, and interpreting results.
- Leadership, matrix decision-making/alignment, publication track record.
- Excellent interpersonal and presentation skills.
Benefits:
- Comprehensive employee benefits package, retirement/savings plan (company contributions), medical/dental/vision, life/disability insurance, flexible spending accounts.
- Discretionary annual bonus (or field sales incentive), stock-based long-term incentives, time-off plans, flexible work models (where possible).
Application Instructions:
- Apply via careers.amgen.com; no application deadline—applications continue until a sufficient number are received or a candidate is selected.