Clinical Development Associate Medical Director- gMG
Vertex Pharmaceuticals
September 01, 2026
Remote friendly (Boston, MA)
United States
Clinical Research and Development
General Summary:
The Clinical Development Associate Medical Director will serve as the Medical Lead for clinical trials, working with cross-functional teams on trial strategy, design, execution, and reporting. Serves as the internal primary Medical Monitor accountable for monitoring the safety of enrolled subjects and ensuring scientific integrity. May participate in other projects to support the clinical development program.
Key Duties and Responsibilities:
- Develop Study Protocols, Investigator’s Brochures, Clinical Development Plans and other key documents with minimal guidance.
- Serve on cross-functional Study Execution Teams (SET) to achieve efficient, high-quality study execution.
- Prepare regulatory documents (e.g., IND/CTA clinical sections, IND safety and annual reports, responses to regulatory authorities and Ethics Committees/IRBs).
- Provide scientific/clinical input to study documents and analysis plans (e.g., informed consent forms, statistical analysis plans, clinical pharmacology analysis plans, clinical study reports).
- Liaise between Clinical Development and internal groups (e.g., Regulatory Affairs, Clinical Development Execution).
- Represent the company to outside medical personnel for protocol development, study conduct, and external reporting of results.
Knowledge and Skills (Required/Preferred):
- Strong oral and written communication; collaborative in fast-paced matrix environments; independent as appropriate.
- Global clinical research experience and regulatory authority interaction (plus).
- Familiarity with data analysis, biostatistics, pharmacology/pharmacokinetics, GCP, clinical study design, ethics committee/IRB review, and clinical development deliverables.
- Board certification/eligibility and clinical training in a relevant medical specialty (highly desired).
Education and Experience:
- MD, DO, or equivalent ex-US medical degree.
- Typically 8 years of basic or clinical research experience (academic or industry) or equivalent education/experience.
Pay Range:
- $240,000 - $360,000.
Benefits (as stated):
- Eligible for annual bonus and annual equity awards; may be eligible for overtime pay (as required). Total Rewards include medical/dental/vision, paid time off (including week-long summer and winter shutdown), educational assistance/student loan repayment, commuting subsidy, matching charitable donations, and 401(k).
The Clinical Development Associate Medical Director will serve as the Medical Lead for clinical trials, working with cross-functional teams on trial strategy, design, execution, and reporting. Serves as the internal primary Medical Monitor accountable for monitoring the safety of enrolled subjects and ensuring scientific integrity. May participate in other projects to support the clinical development program.
Key Duties and Responsibilities:
- Develop Study Protocols, Investigator’s Brochures, Clinical Development Plans and other key documents with minimal guidance.
- Serve on cross-functional Study Execution Teams (SET) to achieve efficient, high-quality study execution.
- Prepare regulatory documents (e.g., IND/CTA clinical sections, IND safety and annual reports, responses to regulatory authorities and Ethics Committees/IRBs).
- Provide scientific/clinical input to study documents and analysis plans (e.g., informed consent forms, statistical analysis plans, clinical pharmacology analysis plans, clinical study reports).
- Liaise between Clinical Development and internal groups (e.g., Regulatory Affairs, Clinical Development Execution).
- Represent the company to outside medical personnel for protocol development, study conduct, and external reporting of results.
Knowledge and Skills (Required/Preferred):
- Strong oral and written communication; collaborative in fast-paced matrix environments; independent as appropriate.
- Global clinical research experience and regulatory authority interaction (plus).
- Familiarity with data analysis, biostatistics, pharmacology/pharmacokinetics, GCP, clinical study design, ethics committee/IRB review, and clinical development deliverables.
- Board certification/eligibility and clinical training in a relevant medical specialty (highly desired).
Education and Experience:
- MD, DO, or equivalent ex-US medical degree.
- Typically 8 years of basic or clinical research experience (academic or industry) or equivalent education/experience.
Pay Range:
- $240,000 - $360,000.
Benefits (as stated):
- Eligible for annual bonus and annual equity awards; may be eligible for overtime pay (as required). Total Rewards include medical/dental/vision, paid time off (including week-long summer and winter shutdown), educational assistance/student loan repayment, commuting subsidy, matching charitable donations, and 401(k).