Chromatography Principal Scientist

Role Summary

Chromatography Principal Scientist responsible for analytical support to chemistry teams and development of analytical methods for small molecules using HPLC, UHPLC, GC, and potentiometry.

Responsibilities

• Develop specific and robust analytical methods using equipment including HPLC, UHPLC, GC, and be responsible for validating the methods when necessary
• Analyze synthetic molecules mainly by HPLC/UHPLC, GC, potentiometry, and TLC
• Perform quantification of impurities
• Perform mass balance studies
• Design and implement analytical strategies for synthesis intermediates and raw materials
• Develop effective collaborations with others within project teams and between analytical groups
• Generate technical reports independently
• Share knowledge and experience of analytical method development for synthetic molecules
• Introduce innovative analytical approaches to facilitate optimal decision-making
• May serve as a project lead

Qualifications

• A Master’s degree or equivalent in Analytical Chemistry or related field with a minimum of 8 years, or a PhD with minimum of 5 years of experience in the pharmaceutical/biotech industry. A PhD in Analytical Chemistry is preferred.
• Expertise in the operation of LC and GC
• Familiarity with the operation of potentiometry titrator, and TLC from multiple manufacturers
• Extensive experience in method development using HPLC/UPLC and GC
• Experience in analytical method validation
• Record of adhering to and promoting lab safety practices
• Good communications skills

Preferred Qualifications

• In-depth understanding of the separation principles of LC, GC and method development software
• Deep expertise in chromatography method development and trouble shoots
• Knowledge of QbD concepts, specification setting, and cGMP, with experience in contributing to regulatory submission
• Communicates effectively in individual and group settings and collaborate effectively in a multi-disciplinary team setting
• Demonstrated project management skills
• Consistent record of collaboration with scientists and other stakeholders at external enterprises
• Advanced scientific network in the industry and academia
• Record of patents and publications