[China Position] Sr. Principal Scientist, Toxicology

Role: Senior Principal Scientist, Toxicology, supporting nonclinical safety assessment for cell and gene therapy programs, including CAR-T platforms, from discovery through IND-enabling stages. Responsibilities: lead in vivo toxicology studies, interpret safety pharmacology, biodistribution, immune toxicity, and long-term safety data; support risk assessments, regulatory document preparation, and cross-functional collaboration with Pharmacology, CMC, Clinical, and Regulatory teams; mentor junior staff and contribute to nonclinical strategy and study planning. Requirements: Ph.D., DVM, PharmD, or equivalent in Toxicology, Pharmacology, or related; 8+ years in nonclinical toxicology within biotech/pharma R&D; experience with cell/gene therapies, biologics, or advanced modalities preferred; knowledge of GLP toxicology, regulatory standards (FDA, EMA, NMPA, ICH), and IND submission support. High-Value: cell and gene therapies, CAR-T platforms, in vivo nonclinical safety, immune toxicity, biodistribution, insertional mutagenesis, regulatory filings (IND, China IIT), toxicology strategy. Work Setup: not specified, likely on-site or hybrid given industry standards.