Biomarker and Precision Medicine Lead

Role Summary

Lead Biomarker and Precision Medicine efforts within the Translational Medicine Unit to develop and implement translational medicine strategies for Immunology & Inflammation programs. Identify and validate biomarkers that predict patient response, demonstrate molecular activity, and correlate with clinical outcomes. Location: Cambridge, MA; Morristown, NJ.

Responsibilities

• Develop comprehensive biomarker and precision medicine strategies for research and development projects
• Design approaches for implementing biomarkers in clinical studies using various platforms (omics, bioimaging, etc.)
• Provide scientific expertise in translating biological pathways to clinical markers
• Review and interpret complex clinical and non-clinical data sets
• Identify and validate novel biomarkers for patient selection and monitoring
• Lead translational medicine sub-teams and coordinate biomarker identification efforts
• Ensure timely execution of biomarker studies within budget constraints
• Evaluate and select optimal platforms and methodologies for biomarker data generation
• Monitor study progress and troubleshoot technical challenges
• Maintain project documentation and regulatory compliance
• Work closely with multidisciplinary teams including research scientists, clinicians, and data scientists
• Engage with external key opinion leaders and research partners
• Present strategies and results at internal and external meetings
• Contribute to regulatory documents and scientific publications
• Support business development activities related to biomarker strategies

Qualifications

• Required: PhD with at least 5 years of experience in translational and/or clinical research. Will consider MD (or equivalent with similar skill set)
• Required: Demonstrated expertise in immunology, preferably in dermatologic and/or respiratory diseases
• Required: Strong understanding of biomarker development and implementation in clinical trials
• Required: Experience with various biomarker platforms and technologies
• Required: Proven track record in translational research
• Required: Excellence in written and verbal communication
• Preferred: Experience with bioinformatics and computational methods
• Preferred: Knowledge of biomarker assay development for clinical use
• Preferred: Publication record in relevant therapeutic areas
• Preferred: Experience in regulatory interactions