Biologist - In Vivo

Role Summary

Biologist - In Vivo at Lilly Neuroscience, focusing on in vivo pharmacology and pharmacokinetics to support neurodegeneration portfolio and discovery of novel medicines for Alzheimer's disease, Parkinson's disease, ALS, and related conditions. The role involves designing, executing, and analyzing rodent studies, performing dosing and surgical procedures, and collaborating across discovery biology, biomarker, and translational groups.

Responsibilities

• Design, lead, and conduct in vivo studies from initiation through data delivery, including dosing, tissue collection, and sample processing.
• Perform all core in vivo dosing techniques, including intravenous, intraperitoneal, subcutaneous, and intracerebroventricular routes.
• Master and perform rodent surgical techniques for sample collection (e.g., CSF, brain, plasma) and delivery of therapeutics.
• Execute study-specific workflows, including antibody administration, pharmacokinetic sampling, and brain dissection.
• Perform supporting biochemical assays (ELISA, Western blot, etc.) for quantification and biomarker readouts.
• Maintain accurate, organized records of experimental data, protocols, and sample inventories in electronic lab notebooks.
• Communicate study progress and data clearly to project leads and cross-functional teams.
• Ensure compliance with IACUC-approved animal protocols and uphold high standards of animal welfare and laboratory safety.

Qualifications

• 2+ years of post-degree academic or industry experience involving in vivo studies.
• Bachelors or Masters Degree in Biology, Pharmacology, Animal Sciences, Neuroscience, or a related scientific field.
• Authorized to work in the United States on a full-time basis (no work visa sponsorship provided).

Skills

• Strong hands-on skills with rodent handling, dosing, and tissue collection.
• Ability to work independently and within a multidisciplinary team.
• Attention to detail, time management, and robust record-keeping.
• Experience with CSF collection, ICV injections, or stereotaxic surgeries.
• Familiarity with pharmacokinetic or biodistribution studies.
• Knowledge of neurodegenerative disease models (e.g., APP/PS1) and biochemical assays (ELISA, Western blotting).
• Background in drug discovery or preclinical development.
• Strong documentation, communication, and data presentation skills.

Education

• Bachelor‚Äôs or Master‚Äôs Degree in Biology, Pharmacology, Animal Sciences, Neuroscience, or a related field.

Additional Requirements

• Qualified applicants must be authorized to work in the United States on a full-time basis; Lilly will not provide work authorization or visa sponsorship for this role.