Primary Responsibilities
- Method Development: Design and develop analytical methods to characterize lentiviral/AAV vectors, vector-related processes, and on-/off-target genome modifications in engineered T cells.
- Method Life Cycle: Perform phase-appropriate validation, transfer, and bridging of analytical methods, including the training of additional laboratory operators.
- Laboratory Execution: Design and execute complex experiments to support process development.
- Sample & Reagent Management: Oversee sample management, execute routine testing, and manage critical reagents to support ongoing programs.
- Compliance & Documentation: Maintain accurate electronic laboratory notebooks (ELN) and author technical, developmental, and regulatory documents (e.g., study reports, SOPs).
- Collaboration: Partner with team members to support day-to-day laboratory operations, ensuring a smooth, safe, and efficient working environment.
- Communication: Present experimental designs, data, and findings at internal and external meetings.
Basic Qualifications
- B.S. in Molecular Biology (2+ years post-graduate research) OR M.S. in Molecular Biology.
- Proficiency in molecular biology techniques (construct design/cloning, primer/probe design, qPCR, RT-PCR, ddPCR).
- Hands-on mammalian cell culture and cell manipulation (transfection and transduction).
- Ability to adhere to methods/SOPs and design/troubleshoot complex experiments.
- Exceptional documentation skills (experimental records, study reports, SOPs).
- Strong time management and prioritization across multiple projects.
- Responsibility/accountability/integrity; ability to mentor/train operators.
Preferred Qualifications
- 2+ years biotech/pharma industry experience in assay development (or related).
- Hands-on lentiviral infectious titer assay.
- Hands-on qPCR and droplet digital PCR (ddPCR).
- Working knowledge of ELN systems and DNA sequence analysis software.
Compensation (Seattle, WA)
- $82,750 - $100,271 (full-time). Additional incentive cash/stock opportunities may be available (based on eligibility).