Associate Scientist, Protein Expression Sciences

Role Summary

Associate Scientist, Protein Expression Sciences. We are seeking an Associate Scientist to join the Protein Expression Sciences team. In this role, you will be responsible for generating manufacturing grade clinical cell lines for production of therapeutic antibodies to support the Regeneron pipeline.

Responsibilities

• Applying innovative mammalian expression technologies to generate regulatory compliant stable cell lines
• Performing techniques such as aseptic cell culture handling and transfection of cell lines
• Performing of flow cytometry assays and operating liquid handler platforms to analyze stable cell lines
• Performing general molecular biology and protein biochemistry techniques e.g., PCR, RT-PCR, plasmid sub-cloning, isolation of genomic DNA and RNA from CHO cells, SDS-PAGE, western blotting
• Accurately and consistently recording experimental methods, materials, and results in electronic laboratory notebooks

Qualifications

• BS or MS in a scientific field with 0-3 years of proven experience
• Hands-on technical experience in molecular biology and protein biochemistry techniques (PCR, RT-PCR, plasmid sub-cloning, genomic DNA/RNA isolation from CHO cells, SDS-PAGE, western blotting)
• Knowledge of flow cytometry is helpful; training can be provided if necessary
• Experience with functional assays (ELISA, ELISPOT) and molecular biology techniques (DNA/RNA/qRT-PCR, cloning) is a plus