Associate Scientist, Postdoctoral Fellow - Large Molecules
Merck
Full-time
Remote friendly (Lansdale, PA)
United States
Clinical Research and Development
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Role Summary
Associate Scientist, Postdoctoral Fellow - Large Molecules
Responsibilities
- Lead multidisciplinary efforts to evaluate delivery and stability of structurally diverse large molecule APIs through development of biomaterial platforms based on hydrogels.
- Design, prepare, and characterize formulation approaches; evaluate drug release kinetics in vitro; assess stability under accelerated conditions.
- Support design and execution of in vivo studies for preclinical performance; collaborate with colleagues across Pharmaceutical Sciences and other development organizations to address formulation and delivery challenges of biologics and vaccines.
- Present novel findings at internal and external scientific forums and publish in peer-reviewed journals.
- Independently develop and implement scientific ideas in an interdisciplinary environment; share learnings with cross-functional teams.
Qualifications
- Required: Ph.D. in Pharmaceutical Sciences, Chemical Engineering, Chemistry/Biochemistry, Biomedical Engineering, Materials Science and Engineering, or related disciplines (or Ph.D. degree earned by Spring 2026).
- Required: Background in materials science, biomaterials, polymer chemistry, supramolecular materials, protein/vaccine formulations and/or bioconjugation techniques.
- Required: Knowledge and experience in materials and analytical characterization.
- Required: Excellent verbal and written communication skills; strong ability to collaborate in cross-functional teams; independently solve problems; strong scientific acumen.
Skills
- Analytical chemistry
- Drug delivery
- Materials science and characterization techniques (e.g., DLS, SLS, DSC, FTIR, EM, NMR, rheology)
- Biomaterials and supramolecular hydrogels
- Protein science and biochemistry; understanding of molecular liabilities and post-translational modification
- Biophysical/biochemical characterization
- Programming/mathematical modeling (optional)
- Scientific writing and data interpretation
Education
- Ph.D. in relevant field; degree expected by Spring 2026 accepted.