Associate Scientist, Post Doc Fellow
Merck
October 1, 2026
Full-time
Remote friendly (West Point, PA)
Worldwide
Clinical Research and Development
Role: Postdoctoral Research Fellow specializing in polysaccharide conjugate vaccine antigen processing and MHC II-restricted epitope presentation. Objectives include developing innovative mapping approaches to elucidate vaccine mechanisms and optimize design. Responsibilities encompass designing and executing experiments on MHC II-peptide complex formation, isolating and identifying epitopes from human APCs, and assessing T-cell activation, with a focus on vaccine efficacy and MoA. Collaboration spans internal teams and external partners; findings will be communicated via publications and presentations. Requirements: Ph.D. in Immunology, Virology, Biology, Biochemistry, or related discipline, with background in mammalian cell culture, immunological assays (ELISA, Western Blot, Flow Cytometry), and experience in MHC epitope mapping, immunoprecipitation, and mass spectrometry. Preferred skills include knowledge of biophysical techniques, immunology, and biochemical characterization. The position emphasizes independent experimental design, analytical proficiency, and collaboration skills. High-value specifics: vaccine MoA, polysaccharide conjugates, epitope mapping, human APCs, mass spectrometry, immunoassays. Location: West Point, PA, with ~10% travel. Salary: $82,000β$92,000, plus benefits, bonus, and long-term incentives. The role offers a pathway to contribute to vaccine development and scientific advancement within a large pharma setting.