Associate Scientist or Scientist, Immunology

Role Summary

Associate Scientist or Scientist, Immunology. Develop and optimize quantitative cell-based assays to support SAR and MOA studies for novel degraders, using both immortalized and primary cells. Characterize lead molecules in vitro in human and animal primary immune and tissue cell types. Communicate research findings in cross-functional project team meetings.

Responsibilities

• Develop and optimize quantitative cell-based assays to facilitate SAR and MOA studies for novel degraders using both immortalized and primary cells.
• Characterize lead molecules in vitro in human and animal primary immune and tissue cell types.
• Communicate research findings in cross-functional project team meetings.
• Review literature and conference proceedings to identify emerging technologies/assays and execute exploratory efforts for internal validation.
• Maintain good written records of laboratory procedures, expand and maintain cell banks, and uphold high standards of lab citizenship among peers.

Qualifications

• Relevant lab experience in immunology, cell biology, or related field.
• Extensive tissue culture experience with both immortalized and primary human cells.
• Deep knowledge in immunology, especially T-cell biology.
• Extensive hands-on experience with standard molecular and cell biology techniques: DNA construct design, transfection, viral transduction, genetic inhibition, ELISA, MSD, AlphaLISA, Western blot, RT-PCR, and flow cytometry, etc.
• Self-motivated, rigorous, efficient, and solution-oriented to deliver in a fast-paced environment with the ability to learn new areas as needed by project goals.
• Can independently develop/execute experiments and analyze/interpret results with minimal supervision while proactively seeking help and guidance as needed.
• Excellent organizational, verbal, and written communication skills and familiarity with electronic laboratory notebooks (ELN).