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Associate Scientist, in vivo Pharmacology

Stoke Therapeutics
Full-time
On-site
Bedford, MA
Clinical Research and Development

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Role Summary

The Associate Scientist, in vivo Pharmacology, will join Stoke's In Vivo Pharmacology Department. This role offers opportunities to learn new techniques and concepts, be creative, and grow with a growing company. Based in Bedford, MA.

Responsibilities

  • Design and execute routine studies to investigate the PK/PD and efficacy of drug candidates.
  • Perform routine to intermediate handling procedures and injections, monitor animal health, and collect tissues in mice.
  • Perform moderately complex behavioral experiments in animal models.
  • Support the implementation of new animal models.
  • Demonstrate technical proficiency to investigate, identify, develop, optimize, and troubleshoot new methods/ techniques/ instrumentation to address critical project needs.
  • Read and understand scientific literature.
  • Analyze data, author technical reports, and document experiments in an electronic notebook.
  • Participate and present at project team and departmental meetings.
  • Maintain laboratory organization including equipment upkeep and ensure compliance with safety protocols.
  • Collaborate across functional areas.

Qualifications

  • S with 7+ years post-graduate experience or M.S. with 4+ years of experience working in a biotechnology or pharmaceutical company or contract research organization.
  • Experience working with animal disease models.
  • Experience with animal behavioral assays.
  • Experience with subcutaneous and intravenous injections in rodents; intracerebroventricular injection experience a plus.
  • Experience with molecular biology assays such as PCR, ELISA, MSD, BCA, Western Blot (or JESS).
  • Strong organizational skills and attention to detail.
  • Strong verbal and written communication skills.
  • Creative thinking and working well in a team environment.
  • Experience in neuroscience a plus.
  • Experience with ISH/IHC a plus.

Additional Requirements

  • Travel: This position will require approximately 0% travel.