Associate Scientist II, Analytical Development

Role Summary

Vaxcyte is seeking an energetic and talented Associate Scientist II, Analytical Development to support developmental activities in the laboratory as assigned. Location: San Carlos, CA.

Responsibilities

• Assist in the design, execution and interpretation of experiments to analyze drug substances and intermediates such as proteins and carbohydrates including:
• Microplate assays include enzymatic assays.
• HPLC- Especially SEC and RP-HPLC with experience in Chemstation.
• CE and iCIEF ‚Äì Especially with Protein Simple or PA-800 systems.
• Assist in analytical method development of new assays.
• Keep accurate and detailed records of experiments.
• Summarize data and communicate to analytical team.
• Support daily lab operations, sample inventory and sample shipment.
• Work within a team environment and provide support to further team objectives.
• Complete any assigned tasks with high quality and in a timely manner.

Qualifications

• BS in Chemistry, Analytical Chemistry preferred, Organic / Biochemistry considered, with 2+ years of relevant lab experience, or MS with 1+ years of experience. Other combinations of education and/or experience may be considered.
• Ideal candidate will have a background in analytical chemistry principles and hands-on experience with modern analytical instrumentations commonly used in the analysis and characterization of drug candidates. Candidates with other scientific disciplines may be considered based on relevant experience.
• Experience in chemical and biological assays such as colorimetric/fluorometric microplate assays and HPLC.
• Experience working with protein analysis ‚Äì UV-Vis, CE, Bradford etc.
• Experience working with carbohydrate analysis and SEC-MALS a plus.
• Understanding of basic principles of analytical method development/validation/ qualification concepts.
• Attention to detail and excellent skills in record keeping / documentation. Critical thinking and ability to analyze data.
• Strong interpersonal skills: ability to communicate effectively both verbally and in written formats.
• Ability to work under supervision and independently in a fast-paced, cross-functional environment and collaborate effectively with other team members. Eagerness and ability to learn and understand new concepts with ease.

Education

• BS in Chemistry or Analytical Chemistry with 2+ years of relevant lab experience, or MS with 1+ years of experience. Organic/Biochemistry considered if relevant experience is present.