Associate Scientist I, Discovery Chemistry Operations

Role: Associate Scientist in Discovery Chemistry focusing on oligonucleotide conjugation, purification, and characterization. Objectives: support Arrowhead's RNAi therapeutic development by optimizing conjugation methods to biomolecules and small molecules. Responsibilities: perform conjugation reactions, troubleshoot and improve protocols, document lab work, track project progress, and communicate findings. Requirements: Bachelor's in Chemistry or Biochemistry; 0-2 years laboratory experience; proficiency in analytical techniques like HPLC; quick learner of new procedures. Preferred: experience with large-molecule synthesis, especially oligonucleotides, in academic or industry settings; prior synthetic chemistry lab experience. High-Value: biopharma, RNAi therapeutics, oligonucleotide conjugation, small molecule/biotherapeutic modalities, early-stage research. WorkSetup: laboratory-based role in Wisconsin, with a pay range of $60,000-$68,000 USD.