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Associate Scientist, Host Cell Protein (HCP) Analytics

Regeneron
August 19, 2026
On-site
Tarrytown, NY
Clinical Research and Development
What You'll Do
- Purify polyclonal antibodies from rabbit/goat bleeds immunized with host cell protein antigens using affinity chromatography and other standard purification workflows
- Optimize and streamline purification protocols to improve yield, purity, reproducibility, and throughput
- Support ELISA method development, qualification, and troubleshooting for HCP detection and quantitation
- Prepare, aliquot, and manage critical reagents (antibodies, conjugates, standards, buffers) to ensure consistent assay performance
- Document all experimental work in the electronic laboratory notebook (ELN) per defined procedures; provide documentation upon request for internal reviews, tech transfer, or regulatory submissions
- Collaborate with process development, QC, and analytical teams on reagent needs and assay performance criteria
- Contribute to continuous improvement of laboratory workflows and best practices

Must-haves
- BS/MS in Biochemistry, Chemistry, Molecular Biology, or related life science
- Hands-on protein purification experience (affinity chromatography; Protein A/G, antigen-affinity columns; AKTA or equivalent FPLC preferred)
- Working knowledge of ELISA and general immunoassay techniques
- Ability to work independently, manage multiple tasks, and maintain rigorous attention to detail
- Excellent written and verbal communication; team-oriented mindset

Preferred / Nice-to-haves
- Prior ELN experience
- Strong documentation habits

Benefits
- Student Loan Paydown program & Tuition Reimbursement
- Family Care Benefits
- Relocation Assistance
- Inclusion, Culture and Well-Being programs (physical & mental health)

Application
- Apply now