Associate Scientist, Formulation Development

Key Accountabilities / Core Job Responsibilities
- Support formulation and drug product development activities for one or more large molecule biotherapeutics.
- Execute formulation development studies to identify clinical formulations and dosage forms.
- Perform hands-on characterization of protein therapeutics using chromatography, capillary electrophoresis, and spectroscopy.
- Understand key degradation mechanisms for each therapeutic.
- Conduct clinical in-use compatibility studies.
- Support drug product process development, including lyophilization.
- Translate analytical results into robust, stable formulations ensuring product quality.
- Author technical documents (formulation development reports; stability protocols/reports).
- Maintain accurate/timely experiment records in an electronic laboratory notebook (ELN).
- Contribute to building formulation capabilities; present results in team meetings.

Qualifications / Skills
- BS or MS in Biochemistry, Chemical/Biochemical Engineering, Pharmaceutical Sciences, or related field; 2+ years relevant CMC experience in biotech/pharma.
- Experience with formulation development, compatibility, stability studies, and buffer exchange.
- Preferred: high concentration protein formulations and/or lyophilization.
- Hands-on experience with chromatography, capillary electrophoresis, spectroscopy, and/or particle analysis.
- Strong collaboration; ability to manage priorities in a fast-paced environment.
- Excellent lab practice, critical thinking/problem-solving, organization, and written/verbal communication.
- Motivated, detail-oriented, naturally curious.

Compensation / Benefits
- Salary range: $106,000–$138,000. Total rewards include 401(k), healthcare coverage, ESPP, and other benefits.

Application instructions
- Learn more at https://www.denalitherapeutics.com/careers