Associate Scientist – Drug Formulation

Associate Scientist, Drug Formulation

What You’ll Do
- Develop, optimize, and characterize nanoparticle (NP)-based drug delivery systems for RNA/gene-based therapeutics.
- Work on formulation and characterization of lipid nanoparticles (LNPs) and other NP delivery systems.
- Design and execute formulation studies, including nucleic-acid encapsulation, analytical testing, and stability evaluations.
- Perform physicochemical characterization (e.g., size, PDI, zeta potential, encapsulation efficiency, drug loading, release kinetics).
- Use analytical methods such as DLS, NTA, UV-Vis spectroscopy, SEC, SDS-PAGE, HPLC, and fluorescence-based assays.
- Support protein bioconjugate work (design/synthesis/purification) and evaluate conjugates (stability, efficiency, binding).
- Troubleshoot formulation challenges and propose data-driven solutions.
- Conduct data/statistical analysis (Excel, GraphPad Prism); maintain electronic notebook records and write internal technical reports.

Qualifications
- BS/MS in Pharmaceutics, Chemistry, Biomedical Engineering, Chemical Engineering, or related field.
- 2+ years of experience.
- Hands-on experience with nanoparticle-based formulation development and analytical characterization.

Nice to Have
- Nucleic-acid delivery experience (lipid/polymeric); nucleic-acid encapsulation techniques.
- Bioconjugate/targeted delivery experience.
- Stability testing, release profiling, formulation optimization.
- Independent experimental design/execution and presentation.

Where You’ll Work / Travel
- Bridgewater, NJ; full-time, in-person. Minimal travel.

Pay Range
- $103,000.00–131,000.00 annual.

Application Instructions
- Current Insmed employees: apply via Jobs Hub in Workday.