Associate Scientist
Cytokinetics
August 22, 2026
Remote friendly (San Francisco Bay Area)
United States
Clinical Research and Development
Key Responsibilities:
- Design, execute, and manage in vivo pharmacology studies and downstream biochemical and molecular assays to evaluate the efficacy of small-molecule therapeutics for cardiac indications.
- Lead day-to-day oversight of animal study cohorts, including scheduling, dosing, monitoring, and coordination with vivarium staff, ensuring full compliance with IACUC and institutional guidelines.
- Quantify and interpret biomarkers of disease progression and target engagement, integrating functional and molecular endpoints to assess compound performance.
- Collaborate with discovery, DMPK, and translational teams to advance compounds through preclinical development, contributing to study design, data interpretation, and go/no-go decisions.
- Maintain rigorous documentation; manage datasets; prepare clear data summaries and presentations for internal project team meetings and program reviews.
Qualifications:
- BS in Biology, Physiology, Pharmacology, or related discipline with 8+ years hands-on research experience, or MS with 6+ years; prior pharmaceutical/biotech experience strongly preferred.
- Demonstrated rodent handling and dosing (mouse and rat) with multiple routes of administration required.
- Cardiac functional assessment experience (e.g., echocardiography, tail-cuff blood pressure) highly desirable.
- Extensive experience with biochemical/molecular biology assays (Western blotting, qPCR, immunohistochemistry, enzyme-based assays).
- Experience with mammalian cell culture or primary cardiomyocytes a plus.
- Ability to analyze, interpret, and clearly communicate complex datasets (written and oral).
Pay Range (U.S.): $121,500–$141,750 per year.
- Design, execute, and manage in vivo pharmacology studies and downstream biochemical and molecular assays to evaluate the efficacy of small-molecule therapeutics for cardiac indications.
- Lead day-to-day oversight of animal study cohorts, including scheduling, dosing, monitoring, and coordination with vivarium staff, ensuring full compliance with IACUC and institutional guidelines.
- Quantify and interpret biomarkers of disease progression and target engagement, integrating functional and molecular endpoints to assess compound performance.
- Collaborate with discovery, DMPK, and translational teams to advance compounds through preclinical development, contributing to study design, data interpretation, and go/no-go decisions.
- Maintain rigorous documentation; manage datasets; prepare clear data summaries and presentations for internal project team meetings and program reviews.
Qualifications:
- BS in Biology, Physiology, Pharmacology, or related discipline with 8+ years hands-on research experience, or MS with 6+ years; prior pharmaceutical/biotech experience strongly preferred.
- Demonstrated rodent handling and dosing (mouse and rat) with multiple routes of administration required.
- Cardiac functional assessment experience (e.g., echocardiography, tail-cuff blood pressure) highly desirable.
- Extensive experience with biochemical/molecular biology assays (Western blotting, qPCR, immunohistochemistry, enzyme-based assays).
- Experience with mammalian cell culture or primary cardiomyocytes a plus.
- Ability to analyze, interpret, and clearly communicate complex datasets (written and oral).
Pay Range (U.S.): $121,500–$141,750 per year.