Associate Scientist - Analytical & Bioanalytical Mass Spectrometry (ABMS)
Regeneron
2 months ago
On-site
Tarrytown, NY
Clinical Research and Development
Associate Scientist — Analytical & Biological Mass Spectrometry (ABMS)
Responsibilities:
- Develop and optimize liquid chromatography coupled to mass spectrometry (LC-MS) methods for enrichment, detection, quantification, and structural characterization of siRNAs, oligonucleotides, novel siRNA conjugates, and monoclonal antibodies (mAbs)
- Perform analytical testing and sample preparation for siRNAs/oligonucleotides, including chromatographic fractionation, LC, LC-MS, solid phase extraction (SPE), hybridization-capture, and related MS methods
- Independently conduct sample preparation and LC-MS analyses in compliance with SOPs/drafted protocols and document procedures/results in an electronic laboratory notebook (ELN)
Qualifications:
- BS or MS in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field
- 0–3 years of relevant hands-on laboratory experience in analytical chemistry or bioanalytical sciences
- Strong hands-on liquid chromatography experience (reversed-phase, size-exclusion, ion exchange); HPLC or UPLC essential
Preferred/Plus:
- Hands-on experience with biological matrices
- Hands-on experience with fractionation, solid phase extraction, and/or hybridization techniques
- Mass spectrometry experience beneficial (ability to optimize separation methods is key)
Application Instructions:
- Apply now
Benefits (explicitly described):
- Health and wellness programs (medical, dental, vision, life, disability), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees (U.S.)
Salary Range (annually):
- $93,900.00 - $153,300.00
Responsibilities:
- Develop and optimize liquid chromatography coupled to mass spectrometry (LC-MS) methods for enrichment, detection, quantification, and structural characterization of siRNAs, oligonucleotides, novel siRNA conjugates, and monoclonal antibodies (mAbs)
- Perform analytical testing and sample preparation for siRNAs/oligonucleotides, including chromatographic fractionation, LC, LC-MS, solid phase extraction (SPE), hybridization-capture, and related MS methods
- Independently conduct sample preparation and LC-MS analyses in compliance with SOPs/drafted protocols and document procedures/results in an electronic laboratory notebook (ELN)
Qualifications:
- BS or MS in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field
- 0–3 years of relevant hands-on laboratory experience in analytical chemistry or bioanalytical sciences
- Strong hands-on liquid chromatography experience (reversed-phase, size-exclusion, ion exchange); HPLC or UPLC essential
Preferred/Plus:
- Hands-on experience with biological matrices
- Hands-on experience with fractionation, solid phase extraction, and/or hybridization techniques
- Mass spectrometry experience beneficial (ability to optimize separation methods is key)
Application Instructions:
- Apply now
Benefits (explicitly described):
- Health and wellness programs (medical, dental, vision, life, disability), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees (U.S.)
Salary Range (annually):
- $93,900.00 - $153,300.00