Associate Scientist - Analytical and Biological Mass Spectrometry (ABMS)
Regeneron
6 months ago
On-site
Tarrytown, NY
Operations
Associate Scientist (Analytical and Biological Mass Spectrometry Group, ABMS)
Responsibilities:
- Execute established protocols and communicate analytical characterization of biotherapeutics (monoclonal and bispecific antibodies, Fc-fusion proteins, and other modalities including AAV and siRNA) to support drug development.
- Perform intact-mass LC-MS characterization to elucidate critical quality attributes (charge variants, size variants, post-translational modifications).
- Provide analytical support to cross-functional teams (formulation development, upstream/downstream process development, manufacturing) to solve drug development challenges.
- Independently conduct sample preparation and LC-MS analyses in compliance with SOPs.
- Document experimental procedures and results in an electronic laboratory notebook (ELN); manage and visualize data and deliver timely updates.
Qualifications / Required:
- Bachelor’s or master’s degree in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a closely related field.
Skills / Preferred:
- Familiarity with advanced mass spectrometers (Q Exactive Plus, Q Exactive UHMR, Q-TOF, etc.), liquid chromatography, liquid-handling systems, and data processing software (Skyline, Protein Metrics, etc.).
- Exposure to automated liquid-handling systems (e.g., Bravo, KingFisher) is a plus; willingness to learn.
- Thrives in a fast-paced, collaborative environment; self-motivated with ability to prioritize and drive work forward with minimal supervision.
Benefits (U.S. may include):
- Health and wellness programs (medical, dental, vision, life, disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave).
Application Instructions:
- Apply now.
Responsibilities:
- Execute established protocols and communicate analytical characterization of biotherapeutics (monoclonal and bispecific antibodies, Fc-fusion proteins, and other modalities including AAV and siRNA) to support drug development.
- Perform intact-mass LC-MS characterization to elucidate critical quality attributes (charge variants, size variants, post-translational modifications).
- Provide analytical support to cross-functional teams (formulation development, upstream/downstream process development, manufacturing) to solve drug development challenges.
- Independently conduct sample preparation and LC-MS analyses in compliance with SOPs.
- Document experimental procedures and results in an electronic laboratory notebook (ELN); manage and visualize data and deliver timely updates.
Qualifications / Required:
- Bachelor’s or master’s degree in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a closely related field.
Skills / Preferred:
- Familiarity with advanced mass spectrometers (Q Exactive Plus, Q Exactive UHMR, Q-TOF, etc.), liquid chromatography, liquid-handling systems, and data processing software (Skyline, Protein Metrics, etc.).
- Exposure to automated liquid-handling systems (e.g., Bravo, KingFisher) is a plus; willingness to learn.
- Thrives in a fast-paced, collaborative environment; self-motivated with ability to prioritize and drive work forward with minimal supervision.
Benefits (U.S. may include):
- Health and wellness programs (medical, dental, vision, life, disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave).
Application Instructions:
- Apply now.