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Associate Scientist

Crinetics Pharmaceuticals
Full-time
On-site
San Diego, CA
$107,000 - $134,000 USD yearly
Clinical Research and Development

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Role Summary

The Associate Scientist, In Vivo Pharmacology will work collaboratively and be responsible for performing a variety of pre-clinical in vivo experiments to advance small molecule therapeutics for endocrine disorders and endocrine-related cancers.

Responsibilities

  • Design and conduct pre-clinical in vivo experiments to evaluate the pharmacodynamics, pharmacokinetics, and safety of therapeutic candidate molecules.
  • Develop new animal models for evaluating novel small molecules for endocrine diseases.
  • Demonstrate initiative to troubleshoot and accurately perform in vivo studies.
  • Ensure care and welfare of laboratory animals in accordance with regulations and IACUC protocols.
  • Generate and manage purchase orders, contracts, and other related documents.
  • Present findings at team and departmental meetings.
  • Perform animal husbandry to conduct biological assays.
  • Run and troubleshoot biomarker assays such as ELISAs and LUMINEX assays.
  • Analyze experimental data using MS Office, PRISM, or comparable software.
  • Comply with company practices and procedures, including notebooks, files, quality and regulatory guidelines, and safety standards.
  • Other duties as assigned.

Qualifications

  • Bachelor’s in Biology, Pharmacology, Neuroscience, Toxicology or related discipline with a minimum of 8 years of relevant experience, or Master’s degree with a minimum of 6 years of relevant experience.
  • Proven hands-on proficiency in rodent handling and in vivo skills (dosing, blood and tissue collection, necropsy, etc.) and experience designing/conducting rodent in vivo pharmacology studies.
  • Experience with ELISA and biomarker assays.
  • Proficient in basic surgical techniques in rodents.
  • Ability to follow pre-established experimental designs and develop new methods or protocols as needed.
  • Strong communication skills and ability to present results to team members.
  • Strong organizational skills with attention to detail and problem-solving abilities.
  • Strong work ethic and ability to multi-task and engage in animal and laboratory work.

Skills

  • In vivo pharmacology
  • Biomarker assays (ELISA, LUMINEX)
  • Animal handling and surgical techniques in rodents
  • Data analysis (MS Office, PRISM)
  • Regulatory compliance and IACUC protocols

Education

  • Bachelor’s or Master’s degree in a relevant life science field as specified in Qualifications.

Additional Requirements

  • Travel up to 5% of time.
  • Physical ability to perform laboratory and animal handling tasks as described.
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