Associate Scientist- 3D Engineered In Vitro Models

Role Summary

Associate Scientist- 3D Engineered In Vitro Models. The role is in the Translational Models group within the Human Biology department in GSK’s Research Technologies organization at the Upper Providence site, focusing on developing preclinical 3D cell and tissue models to improve predictive value and support reduction of animal studies.

Responsibilities

• Perform assays to characterize cells, organoids, microphysiological systems and 3D bio printed constructs.
• Fabricate and test microfluidic devices for cell and tissue phenotypes.
• Maintain inventory of cells, reagents and assays to support a matrix team in a cross-functional environment to ensure optimal delivery of project and department objectives to the highest possible scientific standard.
• Support protocol development, maintenance of laboratory equipment and conduct routine experiments to advance therapeutic pipeline.

Qualifications

• Bachelor’s in biomedical engineering, Bioengineering, Chemical Engineering, Biomedical Sciences or related discipline.
• 1+ years’ experience in primary cells, induced pluripotent stem cells and tissue-derived stem cells.
• Experience with biological assays including imaging-based analysis.
• Masters degree (preferred).
• 3+ years of experience in microfabrication and microfluidics based in vitro models (preferred).
• Experience in supporting research and development of multicellular 3D in vitro models (preferred).
• Significant laboratory work with histopathology, flow cytometry/FACS, ELISA/Luminex/MSD, qPCR and confocal microscopy (preferred).
• Prior knowledge on integration of automation technologies with microfabricated systems (preferred).
• Experience with CAD, MS Office, complex data analysis and statistical software (preferred).
• Excellent written and oral communication skills (preferred).