Role Summary
The Associate Scientist, In Vivo Pharmacology will work collaboratively and be responsible for performing a variety of pre-clinical in vivo experiments to advance small molecule therapeutics for endocrine disorders and endocrine-related cancers.
Responsibilities
- Design and conduct pre-clinical in vivo experiments to evaluate the pharmacodynamics, pharmacokinetics, and safety of therapeutic candidate molecules.
- Develop new animal models for evaluating novel small molecules for endocrine diseases.
- Demonstrate initiative to troubleshoot and accurately perform in vivo studies.
- Ensure care and welfare of laboratory animals in accordance with regulations and IACUC protocols.
- Generate and manage purchase orders, contracts, and other related documents.
- Present findings at team and departmental meetings.
- Perform animal husbandry to conduct biological assays.
- Run and troubleshoot biomarker assays such as ELISAs and LUMINEX assays.
- Analyze experimental data using MS Office, PRISM, or comparable software.
- Comply with company practices and procedures, including notebooks, files, quality and regulatory guidelines, and safety standards.
- Other duties as assigned.
Qualifications
- Bachelor’s in Biology, Pharmacology, Neuroscience, Toxicology or related discipline with a minimum of 8 years of relevant experience, or Master’s degree with a minimum of 6 years of relevant experience.
- Proven hands-on proficiency in rodent handling and in vivo skills (dosing, blood and tissue collection, necropsy, etc.) and experience designing/conducting rodent in vivo pharmacology studies.
- Experience with ELISA and biomarker assays.
- Proficient in basic surgical techniques in rodents.
- Ability to follow pre-established experimental designs and develop new methods or protocols as needed.
- Strong communication skills and ability to present results to team members.
- Strong organizational skills with attention to detail and problem-solving abilities.
- Strong work ethic and ability to multi-task and engage in animal and laboratory work.
Skills
- In vivo pharmacology
- Biomarker assays (ELISA, LUMINEX)
- Animal handling and surgical techniques in rodents
- Data analysis (MS Office, PRISM)
- Regulatory compliance and IACUC protocols
Education
- Bachelor’s or Master’s degree in a relevant life science field as specified in Qualifications.
Additional Requirements
- Travel up to 5% of time.
- Physical ability to perform laboratory and animal handling tasks as described.