Associate Scientific Director, Translational Precision Medicine, Neuroscience
AbbVie
3 months ago
Remote friendly (Waltham, MA)
United States
Clinical Research and Development
Purpose:
Translational scientist bridging basic neuroscience and clinical applications to develop biological and disease insights for neurological and psychiatric disorders.
Responsibilities:
- Uncover neurobiological mechanisms explaining patient subtypes, mechanisms of action/response/resistance, and enable novel interventions.
- Develop testable hypotheses on neurobiological pathways, neuronal circuitry, cognitive/behavioral domains, or functional disease/patient markers to advance pipeline and disease-area goals; collaborate with PMed DAS and functional leads to execute operationally sound approaches.
- Shape human neuroscience efforts and promote R&D research synergies aligned to disease-area strategy.
- Drive strategy for translational biomarker development and discovery target validation/MOA projects.
- Lead design of clinically translational experiments with PMED, clinical leads, and discovery translational teams.
- Establish external collaborations to expand translational experimental design.
- Ensure quality/effectiveness of major precision-medicine project plans via sound design and early risk assessment.
- Advance clinical translational efforts through stakeholder alignment and navigation of business challenges.
- Communicate expertise and share learnings with peers and senior management.
- Source and leverage emerging scientific trends inside/outside the organization.
Qualifications:
- BS (Science) +16 yrs; MS +10 yrs; or PhD/terminal degree (or PharmD/MD) +6 yrs in related fields.
- Expertise in biology/target validation/biomarkers (neural circuits, clinical functional domains such as cognitive/emotional/behavioral, liquid-based methods, and/or structural/functional imaging).
- Knowledge of drug development and clinical translation.
- Proven cross-functional leadership.
- Strong presentation skills to scientific and non-scientific audiences.
Benefits (as stated): paid time off; medical/dental/vision insurance; 401(k); eligible for short-term incentive programs.
Translational scientist bridging basic neuroscience and clinical applications to develop biological and disease insights for neurological and psychiatric disorders.
Responsibilities:
- Uncover neurobiological mechanisms explaining patient subtypes, mechanisms of action/response/resistance, and enable novel interventions.
- Develop testable hypotheses on neurobiological pathways, neuronal circuitry, cognitive/behavioral domains, or functional disease/patient markers to advance pipeline and disease-area goals; collaborate with PMed DAS and functional leads to execute operationally sound approaches.
- Shape human neuroscience efforts and promote R&D research synergies aligned to disease-area strategy.
- Drive strategy for translational biomarker development and discovery target validation/MOA projects.
- Lead design of clinically translational experiments with PMED, clinical leads, and discovery translational teams.
- Establish external collaborations to expand translational experimental design.
- Ensure quality/effectiveness of major precision-medicine project plans via sound design and early risk assessment.
- Advance clinical translational efforts through stakeholder alignment and navigation of business challenges.
- Communicate expertise and share learnings with peers and senior management.
- Source and leverage emerging scientific trends inside/outside the organization.
Qualifications:
- BS (Science) +16 yrs; MS +10 yrs; or PhD/terminal degree (or PharmD/MD) +6 yrs in related fields.
- Expertise in biology/target validation/biomarkers (neural circuits, clinical functional domains such as cognitive/emotional/behavioral, liquid-based methods, and/or structural/functional imaging).
- Knowledge of drug development and clinical translation.
- Proven cross-functional leadership.
- Strong presentation skills to scientific and non-scientific audiences.
Benefits (as stated): paid time off; medical/dental/vision insurance; 401(k); eligible for short-term incentive programs.