Associate Principal Scientist, Viral Vector Downstream Process Development

Role: Associate Principal Scientist leading downstream process development for viral vectors in Cell and Gene Therapy, focusing on lentiviral vector (LVV) purification from early R&D through clinical and commercial phases. Responsibilities: define and execute scalable purification strategies, provide technical leadership across clarification, chromatography, UF/DF, and filtration; lead cross-functional project teams; support process scale-up, transfer, and regulatory documentation; drive process characterization, QbD, risk management, and continuous improvement initiatives; and evaluate innovative purification technologies. Requirements: MS with 10+ years or PhD with 7+ years industry experience in downstream biologics process development, with deep expertise in viral vector purification, cGMP, and regulatory standards; proficiency in statistical tools, QbD, and risk assessment; strong leadership and collaboration skills. High-Value: viral vector (preferably LVV) downstream development, cGMP, IND/regulatory support, process transfer to GMP sites, experience with tech transfer, and familiarity with digital tools. Work setup: details not specified, but involves matrix leadership across R&D, manufacturing, QA, and regulatory functions.