Associate Principal Scientist, Upstream Process Development

Role: Associate Principal Scientist in Upstream Process Development focused on biologics manufacturing. Objectives: lead and optimize cell culture processes for early-stage clinical and commercial biologics, ensuring high yield, robustness, scalability, and regulatory readiness. Responsibilities include developing and characterizing upstream processes, collaborating cross-functionally with discovery, downstream, analytical, and manufacturing teams to achieve quality by design, and advancing platform technologies through process improvements and external partnerships. Qualifications: Ph.D. with 4+ years or Master's with 8+ years in chemical or biological engineering, with hands-on experience in mammalian cell culture, CHO cell biology, bioreactor operation, and bioprocess scale-up. Skills: expertise in fed-batch processes, process analytics, statistical methods, and biologics CMC development; strong communication and collaboration skills; track record of scientific publication and innovation. Preferred: experience with advanced process technologies (microbioreactors, high-throughput systems), data science applications, and late-stage process transfer. High-value specifics: focus on biologics, recombinant proteins, mammalian cell culture, process development from lab to pilot scale, and regulatory activities supporting process characterization and validation. Work setup: location not specified, with an expectation of approximately 10% travel.