Associate Director, Viral Vector Process Development, Upstream

Role: Associate Director, Viral Vector Process Development (Upstream), focused on designing, developing, and scaling Lentiviral Vector (LVV) manufacturing processes using suspension bioreactor platforms for cell therapy modalities. Responsibilities include leading upstream process optimization from research to IND enabling, overseeing scale-up strategies from bench to 50–200 L bioreactors, and establishing process characterization and validation for clinical and commercial production. The role involves experimental design, process analytics, technology transfer, team mentorship, and ensuring GMP compliance. Collaboration with internal teams and external vendors is key, notably in sourcing bioreactors and raw materials. Qualifications: PhD in Biochemical Engineering, Virology, or related field with 6+ years (or MS with 10+ years) experience in upstream LVV process development, including scale translation, process characterization, and GMP manufacturing. Technical expertise in suspension-based LVV production, process automation, and regulatory contributions is essential. Preferred: proven success in scaling processes to commercial stages, familiarity with upstream-analytical linkages, and experience with regulatory submissions. The position is based in Gaithersburg, MD, with a focus on operational excellence, process robustness, and cross-functional leadership in a highly collaborative environment.