Associate Director, Translational Science
Legend Biotech
September 01, 2026
Full-time
Remote friendly (Somerset, NJ)
Worldwide
Clinical Research and Development
Role: Associate Director of Translational Science centered on bridging early discovery research with clinical development for cell therapy projects, including CAR-T, TCR-T, and NK cell approaches. Responsibilities: develop and execute translational strategies across autoimmune and oncology indications, analyze multi-omic datasets (scRNA-seq, CITE-seq, spatial transcriptomics), identify biomarkers, and collaborate with clinical teams for assay implementation; manage external partnerships and contribute to scientific communications. Requirements: PhD or MD/PhD in Immunology, Bioinformatics, or related fields; 5+ years in biopharma translational research; deep knowledge of immuno-oncology, auto-immune diseases, and cell therapies; extensive experience with genomic data analysis and biomarker development; understanding of regulatory biomarker requirements. HighValue: cell therapy modalities (CAR-T, TCR-T, NK), autoimmune and oncology disease areas, biomarker discovery/validation, early to Phase II clinical trials, biomarker assay development, regulatory compliance. WorkSetup: based in Somerset, NJ, with potential for collaborative and translational activities across clinical and external sites.