Associate Director, Translational Research

Day One Biopharmaceuticals is an emerging, mission-driven, drug development company intentionally designed to identify, clinically evaluate, and successfully commercialize novel treatments for pediatric oncology patients, and ultimately to expand those benefits to patients of all ages. For more information, please visit our website at http://www.dayonebio.com.

Position Summary

Day One Biopharmaceuticals is seeking an exceptional individual and scientist to support translational research activities across our portfolio of targeted therapeutics for children and adults with cancer. The successful candidate will work closely with cross-functional teams to drive translational research across pipeline programs. This individual will be a key member of the Translational Research group within our Research and Development organization and help us achieve the forward and reverse translational research that is critical to successful pediatric and adult oncology drug development. This position has the potential to be fully remote. Occasional travel will be required for in-person meetings.

Essential Duties And Responsibilities

• Contribute to translational research in oncology, with a focus on patient selection and stratification, pharmacodynamics and biomarker development across all pipeline programs.
• Drive external partnering efforts for preclinical translational research.
• Interface between internal research with external academic or industry partners across programs.
• Select, establish, and manage relationships with external academic partners, including study design of preclinical studies and data analysis, management and generation of study reports.
• Ability to collaborate effectively across Day One departments to engage external leading researchers, build and maintain strong relationships, and identify strategic opportunities for collaboration.
• Contribute to due diligence of new programs or assets to drive pipeline.
• Effectively communicate across functional teams.
• Actively participate in internal and external scientific meetings through presentations and critically evaluate both internal results and emerging scientific literature.
• Keep up to date on relevant scientific literature to apply external learnings to internal programs.

Qualifications

• PhD in cancer biology, pharmacology, cell biology or a related scientific field with 8+ years of drug development in biopharmaceutical industry; or a MS in related field with 15+ years of industry experience.
• Solid track record of research productivity.
• Solid scientific background and understanding of signaling pathways in oncology and ability to translate preclinical concepts to clinical implementation.
• Extensive hands-on experience with relevant assays and techniques.
• Experience in basic in vivo concepts relevant to oncology, including PK-PD and efficacy relationships.
• Experience and demonstrated skills in translating mechanistic biology, in vitro and in vivo pharmacology studies into clinical biomarker, patient stratification, and combination strategies.
• Strong track record of rigorous, detail-oriented approach to study designs, data analysis and interpretation and data communication to cross-functional teams.
• Experience in managing CROs and academic labs.
• Ability to analyze, interpret, and clearly communicate data and its contribution to program development.
• Excellent oral and written communication and presentation skills, and ability to work as an effective team member in highly collaborative, fast-paced start-up biotech work environment.
• Strong analytical skills and problem-solving capabilities.
• Excellent organization skills and ability to manage projects to meet key deliverables.
• Ability to work independently and interact effectively in cross-functional collaborative teams.

Interview Integrity

At Day One, we expect each candidate to engage authentically, representing their true qualifications and experiences. As part of our screening process, we will conduct several interviews and background verification. This ensures candidates have the skills they claim and align with our values. We are excited to learn more about you and to create a genuine experience for everyone.

Compensation And Benefits

The salary range for this position is $175,000 - $200,000. Day One considers a range of factors when determining base compensation. These considerations mean actual compensation will vary. Please visit https://www.dayonebio.com/benefits to see our competitive benefits.

Disclaimer

Day One Biopharmaceuticals is committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law.

Employment is conditioned upon full vaccination from the COVID-19 virus, including submission of documented proof thereof, as of the start date. Day One Biopharmaceuticals will comply with applicable law regarding the reasonable accommodation of individuals who are not vaccinated because of a disability and/or a sincerely held religious belief.

We are unable to sponsor or take over sponsorship of any applicant work visas at this time.

Recruitment & Staffing Agencies

Day One Biopharmaceuticals does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Day One Biopharmaceuticals or its employees is strictly prohibited unless contacted directly by Day One Biopharmaceutical’s internal HR team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Day One Biopharmaceuticals, and Day One Biopharmaceuticals will not owe any referral or other fees with respect thereto.