Associate Director, Translational Medicine , Late Stage Neuroscience

Role Summary

Associate Director, Translational Medicine, Late Stage Neuroscience. Lead translational disease strategies in Alzheimer's and other neurological diseases with deep disease expertise. Manage cross-functional teams and collaborate with translational clinicians, IT, bioinformatics, data science, statistics, external collaborators, and asset leads to develop translational analyses and biomarkers to support late-stage development and lifecycle management. Represent the Neurology Translational Medicine function in internal forums and support publications and scientific communications.

Responsibilities

• Develops and executes translational disease strategy in Alzheimer's / Neurological disease areas with deep disease expertise
• Leads and oversees execution of disease strategy including but not limited to various aspects of patient selection strategies
• Serves as scientific expert in generating novel hypotheses for targetable biologies based on novel discoveries integrating disease work with literature and deep expertise in neuroscience
• Manages cross functional disease project teams with key interfaces in IT, bioinformatics, data science, statistics, external collaborators, contractors, other disease strategy leads and asset leads
• Maintains relationship with translational clinicians for identifying new opportunities and for gaining disease insight
• Identifies needs, gaps and translational disease questions and applies knowledge across all assets in neuroscience area
• Leads small and large collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic, immune and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists, data scientists and statisticians
• Collaborates and guides bioinformatics partners on biological questions to deliver biomarkers and biological understanding from whole transcriptome, whole exome, and/or whole genome data, epigenetics, proteomics, immune profile and single cell data to support drug discovery and development in Alzheimer's / Neurological Diseases
• Manage relationships with key internal stakeholders including regulatory, clinical and commercial and scientific communications and external collaborators to develop translational analysis plans and timelines, and communicate analysis results
• Represent the Neurology Translational Medicine function at internal meetings and provide domain knowledge and disease expertise to cross-functional teams
• Direct and support publications in high quality scientific, technical or medical journals

Qualifications

• Minimum of 8 years post-PhD experience, with demonstrated scientific leadership in integrating, analyzing, and interpreting multimodal biological data in an academic and/or industry setting
• Strong background in neuroscience with focus on Alzheimer's disease, human genetics/genomics, molecular and cellular biology is required. Knowledge in immunology is a plus
• Ability to work in a fast-paced environment with rapidly changing and competing priorities and ambiguity
• Strong team player with the ability to work in cross-functional teams. Excellent communication and collaboration skills
• Strong track record of high-quality scientific publications in relevant fields

Education

• PhD degree in a neuroscience-related field