Associate Director, Study Toxicologist

Key Responsibilities
- Support the design and execution of nonclinical studies, including toxicology, PK, ADME, and bioanalytical studies.
- Provide scientific oversight of outsourced studies (protocol input, study monitoring, data review, and final report review).
- Coordinate study placement and management at CROs (vendor interaction, study startup, timeline tracking).
- Monitor external study conduct to ensure quality and alignment with program timelines/objectives.
- Review and interpret study data/reports for accuracy, completeness, and scientific rigor.
- Partner with Nonclinical Development program leads and cross-functional teams; contribute scientific input to nonclinical development strategy.
- Maintain clear communication with internal stakeholders and external partners.

Qualifications
Required
- PhD (or equivalent) in Toxicology, Pharmacology, DMPK, or a related scientific discipline.
- 10+ years of relevant pharmaceutical/biotechnology industry experience supporting nonclinical development programs.
- Experience managing outsourced nonclinical studies with CROs (protocol and report review).
- Strong attention to detail; ability to manage multiple studies simultaneously.
- Excellent written and verbal communication skills.

Preferred
- Experience with small molecule and/or siRNA programs.
- Experience supporting late-stage nonclinical studies, including DART and carcinogenicity studies.

Compensation/Benefits (as stated)
- Base salary estimate: $178,000–$218,000/year; eligibility for bonus and equity.
- Full-time benefits include flexible paid time off, medical/dental/vision, life/disability, 401(k), and other voluntary benefits.

Application Instructions
- Apply via the Madrigal Careers site (ongoing acceptance).