Associate Director Scientist, Early Oncology Development

Role Summary

The AD Scientist is an important member of the Project Team, working under the supervision of a clinical lead/study physician or senior clinical scientist, supporting activities related to the medical scientific aspects of the compound and its development. The core accountabilities are the medical & scientific support for the development and implementation of early phase AstraZeneca sponsored clinical program strategy, externally sponsored collaborative research program strategy and studies, including clinical science support for initiating clinical trial(s), supporting clinical data review, interpretation of the study results and supporting final recommendations to senior management. As a key member of the Global Project Team, this position demands strong collaborative communication skills, including the ability to engage with and influence a diverse range of stakeholders both within and external to AstraZeneca. You will report to the Senior Group Director Scientist, Early Global Development. The following tasks would be performed under the guidance of the clinical lead, physician or a senior member of the Clinical Science team, with the expectation that over time the AD Scientist would function more independently.

Responsibilities

• Assists with the clinical input to the clinical development plan at all stages of the program.
• Supports the science-to-man sub team (TSST) to integrate the biology, translational and clinical science into the program strategy.
• Supports in developing recommendation(s) on further development strategies to internal committees.
• Supports the preparation of clinical and other data for governance and other presentations.
• Supports the preparation of program level documents such as the investigator's brochure and safety documentation.
• Follows important developments and trends in the medical & scientific literature and disseminates updates to the project team and beyond ensuring all involved parties are aware of key developments and the impact on the strategy, with physician or senior clinical scientist support.
• Supports the collaboration with the Lead Bio-scientist and Translational scientist to provide clinical input to the development and review of data for input to the development of pre-CDID compounds.
• Supports the development and review of content and quality of publications and inputs to development of the publication strategy.

Qualifications

• Minimum 2 years' experience in clinical drug development or medical research within a pharmaceutical/biotech or academic environment.
• Basic knowledge of clinical oncology practice and the science of cancer, with the ability to rapidly acquire knowledge.
• Experience supporting delivery and influencing at senior leadership levels both internally and externally.
• Experience in working and leading in matrix teams.
• Proven ability in problem solving and issues management that is solution focused.
• Experience in collaborating externally, influencing delivery and scientific engagement.

Skills

• MS degree in Clinical, Biomedical, Pharmacy, Nursing or a relevant discipline; advanced education or PhD preferred.
• Strong collaborative communication skills and ability to engage with diverse stakeholders.
• Ability to interpret clinical data and provide scientific input to development strategies.
• Knowledge of regulatory guidelines and GCP compliance.

Education

• MS degree in Clinical, Biomedical, Pharmacy, Nursing or a relevant discipline; advanced education or PhD preferred.