Associate Director, Quantitative Systems Pharmacology

Role: Associate Director of Quantitative Systems Pharmacology (QSP) supporting RNAi therapeutic development across all stages. Responsibilities: lead QSP modeling strategies for dose optimization, trial design, disease mechanisms, and clinical outcome prediction; collaborate with clinical pharmacologists, pharmacometricians, and research teams to interpret data and refine models; build and analyze biological process models; stay current with modeling methodologies; publish and present findings to enhance visibility. Qualifications: Ph.D. in systems biology, pharmacology, biomedical engineering, or related; 5+ years in pharma, consulting, or regulatory settings with proven impact of QSP models on drug development; strong expertise in systems biology, physiology, PK/PD, and differential equation-based modeling; proficient with R, MATLAB, Simbiology; excellent communication and team collaboration skills. High-Value: focus on RNAi therapeutics, advanced modeling techniques, cross-functional R&D collaboration, internal/external scientific dissemination, no specific therapeutic area given, development stage spans all phases. Work setup details not specified, but implied to operate within a matrixed research environment.