Associate Director Quantitative Pharmacology

Role: Associate Director leading model-informed drug development within Quantitative Pharmacology, supporting antibody, siRNA, and gene therapy modalities across early to late-stage development. Responsibilities include designing and executing population PK/PD, exposure–response, and translational modeling analyses, and providing strategic insights for dose selection, trial design, and regulatory submissions. The role involves cross-functional collaboration with Clinical Pharmacology, Biostatistics, and Translational teams, representing Quantitative Pharmacology in program meetings, and contributing to regulatory documents. Mentorship of junior scientists and process innovation are key aspects. Qualifications: PhD in Quantitative Pharmacology, Pharmacometric, Engineering, or related field with 7+ years (PhD) or 10+ years (MS) of relevant industry experience; proficiency in modeling tools such as NONMEM, Monolix, MATLAB, and R; proven track record supporting regulatory submissions and direct agency interactions. High-value specifics include therapeutic areas of antibodies, siRNA, and gene therapies; emphasis on early to late clinical development stages; and a focus on scientific rigor, regulatory compliance, and innovative modeling approaches. The position offers flexible work arrangements (remote or onsite in NY, NJ, MA), with potential for cross-functional influence and high impact on clinical and regulatory strategies.