Associate Director - QSP Quantitative Systems Pharmacology
Sanofi
June 26, 2026
Remote friendly (Morristown, NJ)
United States
$148,500 - $214,500 USD yearly
Clinical Research and Development
Main Responsibilities
- Interface with project teams to align M&S needs and develop QSP strategy to address needs.
- Develop and implement innovative mechanistic modeling strategies to support project team M&S needs.
- Communicate modeling predictions to key stakeholders to inform strategy and decision-making.
- Identify and interpret preclinical and clinical data critical for model development and refinement.
- Stay current with advances in systems pharmacology, disease modeling, and regulatory expectations for model-informed drug development.
- Contribute to abstracts and manuscripts.
- Perform job duties independently with minimal supervision and mentor others to develop similar capabilities.
Qualifications/Required
- Ph.D. in Biomedical Engineering, Applied mathematics, Systems Biology/Pharmacology or related fields.
- 6+ years of hands-on QSP modeling experience in the pharmaceutical/biotechnology industry with demonstrated impact on R&D programs.
- Evidence of independence leading scientific projects; strong QSP modeling publication record.
- Hands-on programming experience with Matlab/R/Julia (Matlab preferred).
- Demonstrated experience creating/using QSP models to influence go/no-go decisions.
- Deep disease biology understanding in at least one therapeutic area; experience applying QSP across multiple programs or drug modalities.
- Experience with heterogeneous datasets (preclinical and clinical).
- Best practices for reproducible, well-documented modeling workflows.
- Proven ability to lead modeling workstreams and communicate quantitative insights to scientific and non-scientific stakeholders.
Preferred
- Experience mentoring junior scientists.
- Understanding of neurology, neuroinflammation and neurodegeneration.
- Exposure to regulatory interactions or documentation involving MIDD.
Benefits
- Health and wellbeing benefits including high-quality healthcare, prevention and wellness programs; at least 14 weeks’ gender-neutral parental leave.
#GD-SA
- Interface with project teams to align M&S needs and develop QSP strategy to address needs.
- Develop and implement innovative mechanistic modeling strategies to support project team M&S needs.
- Communicate modeling predictions to key stakeholders to inform strategy and decision-making.
- Identify and interpret preclinical and clinical data critical for model development and refinement.
- Stay current with advances in systems pharmacology, disease modeling, and regulatory expectations for model-informed drug development.
- Contribute to abstracts and manuscripts.
- Perform job duties independently with minimal supervision and mentor others to develop similar capabilities.
Qualifications/Required
- Ph.D. in Biomedical Engineering, Applied mathematics, Systems Biology/Pharmacology or related fields.
- 6+ years of hands-on QSP modeling experience in the pharmaceutical/biotechnology industry with demonstrated impact on R&D programs.
- Evidence of independence leading scientific projects; strong QSP modeling publication record.
- Hands-on programming experience with Matlab/R/Julia (Matlab preferred).
- Demonstrated experience creating/using QSP models to influence go/no-go decisions.
- Deep disease biology understanding in at least one therapeutic area; experience applying QSP across multiple programs or drug modalities.
- Experience with heterogeneous datasets (preclinical and clinical).
- Best practices for reproducible, well-documented modeling workflows.
- Proven ability to lead modeling workstreams and communicate quantitative insights to scientific and non-scientific stakeholders.
Preferred
- Experience mentoring junior scientists.
- Understanding of neurology, neuroinflammation and neurodegeneration.
- Exposure to regulatory interactions or documentation involving MIDD.
Benefits
- Health and wellbeing benefits including high-quality healthcare, prevention and wellness programs; at least 14 weeks’ gender-neutral parental leave.
#GD-SA